CAJ | 학술논문

目的：观察阿莫西林克拉维酸钾干混悬剂联合复方福尔可定治疗小儿急性细菌性上呼吸道感染的临床疗效。方法选择急性细菌性上呼吸道感染患儿160例，分为治疗组（80例）和对照组（80例），治疗组选用阿莫西林克拉维酸钾干混悬剂（7∶1）＋复方福尔可定口服溶液，对照组选用阿莫西林克拉维酸钾干混悬剂（7∶1）＋肺力咳糖浆。治疗疗程均为7 d，比较治疗前后两组细菌清除率、口腔分泌性 SIgA 和总有效率。结果细菌清除率两组差异无统计学意义（P ＞0．05），治疗后实验组患儿口腔分泌性 SIgA 较治疗前有升高（P ＜0．05），而对照组差异无统计学意义（P ＞0．05），治疗组总有效率93．75％。显著高于对照组86．25％（P ＜0．05），两组患儿均无严重的不良反应发生。结论阿莫西林克拉维酸钾干混悬剂联合复方福尔可定治疗小儿急性细菌性上呼吸道感染疗效显著。
목적：관찰아막서림극랍유산갑간혼현제연합복방복이가정치료소인급성세균성상호흡도감염적림상료효。방법선택급성세균성상호흡도감염환인160례，분위치료조（80례）화대조조（80례），치료조선용아막서림극랍유산갑간혼현제（7∶1）＋복방복이가정구복용액，대조조선용아막서림극랍유산갑간혼현제（7∶1）＋폐력해당장。치료료정균위7 d，비교치료전후량조세균청제솔、구강분비성 SIgA 화총유효솔。결과세균청제솔량조차이무통계학의의（P ＞0．05），치료후실험조환인구강분비성 SIgA 교치료전유승고（P ＜0．05），이대조조차이무통계학의의（P ＞0．05），치료조총유효솔93．75％。현저고우대조조86．25％（P ＜0．05），량조환인균무엄중적불량반응발생。결론아막서림극랍유산갑간혼현제연합복방복이가정치료소인급성세균성상호흡도감염료효현저。
Objective To observe the curative effect of amoxicillin clavulanate combined with compound phol-codine syrup for children with acute bacterial upper respiratory tract infection.Methods One hundred and sixty chil-dren with acute bacterial upper respiratory tract infection were chosen,and divided into treatment group(80 cases) and control group(80 cases)randomly.Amoxicillin clavulanic(7∶1)combined with compound pholcodine syrup were enrolled in the treatment group,while amoxicillin clavulanic(7∶1)combined with lung cough syrup were in the con-trol group.The bacterial clearance rate,oral secretory SIgA and total effective rate were compared before and after the treatment for 7 days.Results There was no significant difference in the bacterial clearance rate in the two groups (P >0.05).The oral secretory SigA increased after treatment comparing with that before treatment(P <0.05)in the treatment group while no significant difference(P >0.05)in the control one.The total effective rate in the treatment group was higher than that in the control one(93.75% vs.86.25%)(P <0.05).No serious side effect occurred in the two groups.Conclusion It has significant effect using amoxicillin clavulanic combined with compound pholcodine syrup in treatment of pediatric acute bacterial upper respiratory tract infection.