CAJ | 학술논문

妊娠对先天性心脏病相关性肺动脉高压患者最重要的影响是血容量的增加、外周循环阻力下降及高凝状态。心功能、运动耐量、肺动脉压力、血氧饱和度和脑钠肽等是监测母体心血管疾病发病率的重要指标。肺动脉高压极易引发肺部微血栓形成，先天性心脏病相关性肺动脉高压患者在产后应给予抗凝治疗。维持相对较高的体循环压力，可减少右向左分流。在围术期使用扩血管药物可提高手术生存率，但在孕期如何用药仍需进一步研究，避免妊娠或适时剖宫产终止妊娠均可获得较好结局。
임신대선천성심장병상관성폐동맥고압환자최중요적영향시혈용량적증가、외주순배조력하강급고응상태。심공능、운동내량、폐동맥압력、혈양포화도화뇌납태등시감측모체심혈관질병발병솔적중요지표。폐동맥고압겁역인발폐부미혈전형성，선천성심장병상관성폐동맥고압환자재산후응급여항응치료。유지상대교고적체순배압력，가감소우향좌분류。재위술기사용확혈관약물가제고수술생존솔，단재잉기여하용약잉수진일보연구，피면임신혹괄시부궁산종지임신균가획득교호결국。
The most important effect on CHD-PAH patients in pregnancy is blood volume increasing,peripheral circulation resistance decreasing and hypercoagulable state.Cardiac function prediction,exercise tolerance,pulmonary artery pressure,oxygen saturation and brain natriuretic peptide are important indicators to monitor maternal cardiovascular morbidity.Pulmonary hypertension can easily lead to pulmonary micro-thrombosis,CHD-PAH patients should be given anticoagulation therapy postpartum.Vasodilator effect on pulmonary hypertension patients,may improve surgical survival.Right to left shunt can be reduced by maintaining a relatively high systemic pressure.It needs further study how to medicate during pregnancy.Avoid pregnancy or timely termination of pregnancy by cesarean plane can obtain better outcome.