CAJ | 학술논문

目的：探讨D-二聚体在急性胰腺炎(AP)临床分型及严重程度评估中的意义。方法选取45例AP患者，将其分为轻度AP(MAP)组22例，中度AP(MSAP)组19例，重度AP(SAP)组4例，入院即刻抽取其静脉血，应用全自动血凝仪，采用免疫比浊法测定D-二聚体含量。入院24 h内完善胰腺增强CT检查，计算MCTSI评分。结果MAP、MSAP、SAP组的D-二聚体含量分别为(588.95±644.44)、(2170.53±3035.69)、(5362.50±2884.26)μg/L；散点图提示D-二聚体含量与MCTSI呈正相关，Spearman秩相关提示两者呈正相关(r=0.593，P<0.01)。结论 D-二聚体与AP严重程度呈正相关，可作为早期判断AP严重程度的指标之一。
목적：탐토D-이취체재급성이선염(AP)림상분형급엄중정도평고중적의의。방법선취45례AP환자，장기분위경도AP(MAP)조22례，중도AP(MSAP)조19례，중도AP(SAP)조4례，입원즉각추취기정맥혈，응용전자동혈응의，채용면역비탁법측정D-이취체함량。입원24 h내완선이선증강CT검사，계산MCTSI평분。결과MAP、MSAP、SAP조적D-이취체함량분별위(588.95±644.44)、(2170.53±3035.69)、(5362.50±2884.26)μg/L；산점도제시D-이취체함량여MCTSI정정상관，Spearman질상관제시량자정정상관(r=0.593，P<0.01)。결론 D-이취체여AP엄중정도정정상관，가작위조기판단AP엄중정도적지표지일。
Objective To discuss the significance of D-dimer in clinical classification and severity of acute pancreatitis (AP). Methods 45 patients with AP were selected and divided into the mild acute pancreatitis (MAP) group (n=22),the moderately severe acute pancreatitis (MSAP) group (n=19) and the severe acute pancreatitis (SAP) group (n=4).On ad-mission,patients were given the venous blood extraction,full automatic blood coagulation analyzer and immunotur-bidimetry were used to the content of D-dimer.Pancreatic enhancement CT examination was improved into the hospital within 24 hours to count the MCTSI score. Results The content of D-dimer of the MAP, MSAP and MAP group was (588.95±644.44), (2170.53±3035.69), (5362.50±2884.26) μg/L respectively;scatterplot suggested that the content of D-dimer was positively associated with MCTSI,Spearman rank correlation suggested that there was a positive correlation between them (r=0.593,P<0.01). Conclusion There was positive correlation between the content of D-dimer and the severity of acute pancreatitis.It could be used as one of the indexes of judging the severity of acute pancreatitis in the early stage.