国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
11期
1505-1507
,共3页
心电图%心肌酶%手足口病
心電圖%心肌酶%手足口病
심전도%심기매%수족구병
Electrocardiograph%Myocardial enzyme%Hand-foot-mouth disease
目的 研究手足口病患儿的心肌酶活性及心电图表现,为临床诊疗提供参考.方法 将120例确诊的手足口病患儿作为观察对象,同时按1:1标准选取120例健康儿童作为对照,所有患儿入院后第二天清晨抽取静脉血行心肌酶检测,同时行常规12导联心电图检查,比较两组患儿治疗前后心电图及心肌酶学的差异.结果 观察组患儿肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、天冬氨酸氨基转移酶(AST)、α羟丁酸脱氢酶(HBDH)水平高于对照组,差异有统计学意义(P＜0.05);治疗前后患儿肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、天冬氨酸氨基转移酶(AST)、α羟丁酸脱氢酶(HBDH)水平逐渐降低(P＜0.05);治疗前患儿心电图异常情况主要有窦性心动过速、ST-T改变、传导阻滞及早搏等,治疗后表现为心电图异常率明显降低,主要表现为T波双向或低平.结论 对心电图和心肌酶的检查可早期发现手足口病患儿的心肌损害,对早期诊疗和预后具有积极意义.
目的 研究手足口病患兒的心肌酶活性及心電圖錶現,為臨床診療提供參攷.方法 將120例確診的手足口病患兒作為觀察對象,同時按1:1標準選取120例健康兒童作為對照,所有患兒入院後第二天清晨抽取靜脈血行心肌酶檢測,同時行常規12導聯心電圖檢查,比較兩組患兒治療前後心電圖及心肌酶學的差異.結果 觀察組患兒肌痠激酶同工酶(CK-MB)、乳痠脫氫酶(LDH)、天鼕氨痠氨基轉移酶(AST)、α羥丁痠脫氫酶(HBDH)水平高于對照組,差異有統計學意義(P＜0.05);治療前後患兒肌痠激酶同工酶(CK-MB)、乳痠脫氫酶(LDH)、肌痠激酶(CK)、天鼕氨痠氨基轉移酶(AST)、α羥丁痠脫氫酶(HBDH)水平逐漸降低(P＜0.05);治療前患兒心電圖異常情況主要有竇性心動過速、ST-T改變、傳導阻滯及早搏等,治療後錶現為心電圖異常率明顯降低,主要錶現為T波雙嚮或低平.結論 對心電圖和心肌酶的檢查可早期髮現手足口病患兒的心肌損害,對早期診療和預後具有積極意義.
목적 연구수족구병환인적심기매활성급심전도표현,위림상진료제공삼고.방법 장120례학진적수족구병환인작위관찰대상,동시안1:1표준선취120례건강인동작위대조,소유환인입원후제이천청신추취정맥혈행심기매검측,동시행상규12도련심전도검사,비교량조환인치료전후심전도급심기매학적차이.결과 관찰조환인기산격매동공매(CK-MB)、유산탈경매(LDH)、천동안산안기전이매(AST)、α간정산탈경매(HBDH)수평고우대조조,차이유통계학의의(P＜0.05);치료전후환인기산격매동공매(CK-MB)、유산탈경매(LDH)、기산격매(CK)、천동안산안기전이매(AST)、α간정산탈경매(HBDH)수평축점강저(P＜0.05);치료전환인심전도이상정황주요유두성심동과속、ST-T개변、전도조체급조박등,치료후표현위심전도이상솔명현강저,주요표현위T파쌍향혹저평.결론 대심전도화심기매적검사가조기발현수족구병환인적심기손해,대조기진료화예후구유적겁의의.
Objective To assess the features of myocardial enzyme and electrocardiograph (ECG) in the children with hand-foot-mouth disease (HFMD).The result of our research maybe could provide a kind of method to diagnose and promote earlier therapy in HFMD.Methods This was a cross-sectional study of analyzing 120 children diagnosed as HFMD,while another 120 healthy children were defined as the control group.All participants had the ECG examination and were taken the blood sample to test the myocardial enzyme level before and after the treatment.ECG and myocardial enzyme level in two groups were respectively performed.Results Creatine kinase (CKMB),lactate dehydrogenase (LDH),acid aspartate aminotransferase (AST),α hydroxybutyrate dehydrogenase High (HBDH) Horizontal in children with HFMD were higher in contrast to those of the control group,and the differences were statistically significant (P ＜ 0.05).CK-MB,LDH,CK,AST,HBDH levels decreased when the children got the treatment (P ＜ 0.05).Before getting the treatment,ECG abnormalities of the children with HFMD mainly concluded tachycardia,ST-T changes in conduction block and premature contraction,etc.,which showed significantly lower rates of appearance after being treated,but someone still had a two-way or flat T waves.Conclusion As for the earlier diagnosis,treatment and improving the prognosis of HFMD,it is great valuable to have the ECG examination to test myocardial enzyme level earlier.
