CAJ | 학술논문

目的：观察癃清片对慢性前列腺炎（湿热瘀阻证）伴勃起功能障碍（Erectile Dysfunction，ED）的治疗效果。方法：108例慢性前列腺炎伴发 ED 患者，治疗前行美国国立卫生院慢性前列腺炎症状评分（NIH -CPSI）及国际勃起功能指数问卷5（IIEF -5）评分。将108例患者随机分为对照组（54例）、治疗组（54例）。对照组使用盐酸特拉唑嗪片（马沙尼），口服，2 mg/次，睡前1次，连续治疗8周。治疗组使用癃清片，口服，6片/次，2次/d，连续治疗8周。结果：治疗8周后，对照组 NIH -CPSI 评分（13.0±5.5）分，较治疗前（21.3±2.2）分，差异有统计学意义（P ＜0.05）；IIEF -5评分（12.4±3.4）分，较治疗前（13.5±3.4）分，有所增加但差异无统计学意义（P ＞0.05）；治疗组 NIH -CPSI 评分（12.4±5.4）分，IIEF -5评分（16.2±4.3）分，与治疗前比较，差异有统计学意义（P ＜0.05）。对照组 ED 总有效率为32.65％，治疗组 ED 总有效率为68.63％，其差异有统计学意义（P ＜0.01）。结论：癃清片治疗慢性前列腺炎（湿热瘀阻证）伴发 ED，既可明显改善慢性前列腺炎的症状，同时，对伴发的 ED也有较好的疗效，值得在临床上推广使用。
목적：관찰륭청편대만성전렬선염（습열어조증）반발기공능장애（Erectile Dysfunction，ED）적치료효과。방법：108례만성전렬선염반발 ED 환자，치료전행미국국립위생원만성전렬선염증상평분（NIH -CPSI）급국제발기공능지수문권5（IIEF -5）평분。장108례환자수궤분위대조조（54례）、치료조（54례）。대조조사용염산특랍서진편（마사니），구복，2 mg/차，수전1차，련속치료8주。치료조사용륭청편，구복，6편/차，2차/d，련속치료8주。결과：치료8주후，대조조 NIH -CPSI 평분（13.0±5.5）분，교치료전（21.3±2.2）분，차이유통계학의의（P ＜0.05）；IIEF -5평분（12.4±3.4）분，교치료전（13.5±3.4）분，유소증가단차이무통계학의의（P ＞0.05）；치료조 NIH -CPSI 평분（12.4±5.4）분，IIEF -5평분（16.2±4.3）분，여치료전비교，차이유통계학의의（P ＜0.05）。대조조 ED 총유효솔위32.65％，치료조 ED 총유효솔위68.63％，기차이유통계학의의（P ＜0.01）。결론：륭청편치료만성전렬선염（습열어조증）반발 ED，기가명현개선만성전렬선염적증상，동시，대반발적 ED야유교호적료효，치득재림상상추엄사용。
Objective:To observe the therapeutic effect of Longqing tablets in treating chronic prostatitis (damp-heat stasis obstruction pattern)accompanying erectile dysfunction.Methods:One hundred and eight patients with chronic prostatitis accompanying ED were given the U.S.National Institutes of Health chronic prostatitis symptom score (NIH-CPSI)and the International Index of Erectile Func-tion questionnaire 5 (IIEF-5)score before treatment.All the patients were randomly divided into control group (n =54),the treatment group (n =54).Control group applied oral administration of terazosin hydrochloride tablets (semaxanib),2 mg per time before bedtime consecutively for 8 weeks.Treatment group applied oral administration of Longqing tablets,6 pills per time,2 times a day for 8 weeks. Results:After 8 weeks of treatment,NIH-CPSI score of patients in the control group was 13.0 ±5.5 points,which was significantly improved compared with that before treatment (21.3 ±2.2 points)(P <0.05);IIEF-5 score was 12.4 ±3.4 points which showed no significant improvement compared with that before treatment (13.5 ±3.4 points),(P >0.05);NIH-CPSI score of patients in the treatment group was 12.4 ±5.4 points,and IIEF-5 score was 16.2 ±4.3points,both of which showed significant improvement com-pared with what it was before the treatment (P <0.05).The total effective rate for ED of the control group was 32.65%,and that of the treatment group was 68.63%,and the difference between the two groups was significant (P <0.01 ).Conclusion:Application of Longqing tablets in treating chronic prostatitis (heat stasis)associated with ED can significantly improve symptoms of chronic prostatitis, and meanwhile shows good effect ED,hence it is worth being generalized in clinical practice.