CAJ | 학술논문

目的：探讨婴幼儿静脉留置针输注葡萄糖酸钙时的药物最佳稀释浓度和静脉留置针留置时间。方法选择需要静脉补钙的患儿139例，按随机数字表法分为等倍稀释组43例，2倍稀释组48例和5倍稀释组48例，均使用静脉留置针，比较各组患儿穿刺血管外渗性损伤发生率、损伤程度和愈后情况。结果等倍稀释组、2倍稀释组、5倍稀释组患儿静脉留置针穿刺血管3d累计发生外渗率分别为19．4％，9．0％，2．1％，差异有统计学意义（H＝261．23，P＜0．01）；进一步两两比较，等倍稀释组发生血管外渗率高于2倍稀释组（χ2＝6．88，P＜0．01），2倍稀释组高于5倍稀释组（χ2＝6．40，P＜0．05），等倍稀释组高于5倍稀释组（χ2＝20．48，P＜0．01）。留置针在第1天，第2天，第3天血管外渗率比较差异无统计学意义（H＝3．47，P＞0．05）。结论运用静脉留置针对婴幼儿进行补钙时，10％葡萄糖酸钙稀释5倍时外渗性损伤发生率最低。
목적：탐토영유인정맥류치침수주포도당산개시적약물최가희석농도화정맥류치침류치시간。방법선택수요정맥보개적환인139례，안수궤수자표법분위등배희석조43례，2배희석조48례화5배희석조48례，균사용정맥류치침，비교각조환인천자혈관외삼성손상발생솔、손상정도화유후정황。결과등배희석조、2배희석조、5배희석조환인정맥류치침천자혈관3d루계발생외삼솔분별위19．4％，9．0％，2．1％，차이유통계학의의（H＝261．23，P＜0．01）；진일보량량비교，등배희석조발생혈관외삼솔고우2배희석조（χ2＝6．88，P＜0．01），2배희석조고우5배희석조（χ2＝6．40，P＜0．05），등배희석조고우5배희석조（χ2＝20．48，P＜0．01）。류치침재제1천，제2천，제3천혈관외삼솔비교차이무통계학의의（H＝3．47，P＞0．05）。결론운용정맥류치침대영유인진행보개시，10％포도당산개희석5배시외삼성손상발생솔최저。
Objective To explore the optimum dilution concentration of calcium gluconate intravenous infusion in infants and the detaining time of venous indwelling needle .Methods One hundred and thirty-nine infants who needed calcium gluconate intravenous infusion were chosen and divided into the one time dilution group (n=43), two times dilution group (n=48), and five times dilution group (n=48).The incidence of extravasation injury in puncture vascular , the degree of injury and the situation of healing were compared among three groups .Results The total incidence of extravasation injury in puncture vascular in the one time dilution group, two times dilution group , five times dilution group within 3 days were respectively 19.4%, 9.0%, 2.1%, and the differences were statistically significant (H=261.23, P<0.01).The further analysis showed that the incidence of extravasation injury in the one time dilution group was higher than that of two times dilution group (χ2 =6.88, P<0.01), and the incidence in the two times dilution group was higher than that of five times dilution group (χ2 =6.40, P<0.05), and the incidence in the one time dilution group was higher than that of five times dilution group (χ2 =20.48, P <0.01 ).No difference was found in the incidence of extravasation injury in puncture on the first , second and third day of the detaining time of venous indwelling needle (H=3.47,P>0.05).Conclusions The incidence of extravasation injury is lowest in 5 times diluted concentration of 10%calcium gluconate intravenous infusion in infants through venous indwelling needle .