CAJ | 학술논문

目的：观察戒烟干预对慢性气道疾病发病和预后的影响。方法将145例吸烟的慢性气道疾病住院患者（包括COPD、哮喘、间质性肺疾病等）按照区组随机化法分为两组，干预组75例，非干预组70例。干预组除常规治疗外，采用5 A/5 R法进行戒烟干预，出院后继续给予戒烟支持；非干预组仅进行常规治疗，两组患者通过复诊或随访12个月，统计观察期内急性加重次数，并在入院时和观察期结束时进行COPD评估测试（CAT）及肺功能（FEV1％）检查。结果干预组患者的CAT终末值为（17．72±6．76）分，较初始值（19．08±6．53）分明显下降，差异有统计学意义（t＝-2．399，P＜0．05），FEV1％终末值为（59．19±11．19），较初始值（57．10±10．06）明显增大，差异有统计学意义（t＝2．192，P＜0．05）。非干预组患者的CAT终末值为（20．01±7．22）分，较初始值（18．79±6．12）分增大，差异有统计学意义（t＝2．764，P＜0．05），FEV1％终末值为（54．56±10．56），较初始值（59．06±9．89）降低，差异有统计学意义（t＝-3．038，P＜0．05）。结论戒烟干预可减轻慢性气道疾病患者的症状，延缓肺功能的下降，提高生活质量。
목적：관찰계연간예대만성기도질병발병화예후적영향。방법장145례흡연적만성기도질병주원환자（포괄COPD、효천、간질성폐질병등）안조구조수궤화법분위량조，간예조75례，비간예조70례。간예조제상규치료외，채용5 A/5 R법진행계연간예，출원후계속급여계연지지；비간예조부진행상규치료，량조환자통과복진혹수방12개월，통계관찰기내급성가중차수，병재입원시화관찰기결속시진행COPD평고측시（CAT）급폐공능（FEV1％）검사。결과간예조환자적CAT종말치위（17．72±6．76）분，교초시치（19．08±6．53）분명현하강，차이유통계학의의（t＝-2．399，P＜0．05），FEV1％종말치위（59．19±11．19），교초시치（57．10±10．06）명현증대，차이유통계학의의（t＝2．192，P＜0．05）。비간예조환자적CAT종말치위（20．01±7．22）분，교초시치（18．79±6．12）분증대，차이유통계학의의（t＝2．764，P＜0．05），FEV1％종말치위（54．56±10．56），교초시치（59．06±9．89）강저，차이유통계학의의（t＝-3．038，P＜0．05）。결론계연간예가감경만성기도질병환자적증상，연완폐공능적하강，제고생활질량。
Objective To study the effect of smoking cessation intervention on acute exacerbation and the prognosis of chronic airway diseases .Methods A total of 145 current smokers with chronic airway diseases ( COPD, asthma and interstitial lung disease ) were randomly divided into two groups .The intervention group received smoking cessation interventions by 5A/5R method besides conventional treatment , and the control group only received conventional therapy .The follow-up study was done by 12 months after discharge .The number of acute exacerbation during the observation period and the COPD assessment test ( CAT) and pulmonary function of FEV1% were examined at admission and the end of the intervention period .Results In the intervention group, the terminal CAT score was (17.72 ±6.76), which was significantly lower than the former score of (19.08 ±6.53) (t=-2.399, P<0.05).The terminal value of FEV1%was (59.19 ±11.19), which was also significantly lower than the former score of (57.10 ±10.06) (t=2.192,P<0.05).In the control group, the terminal CAT score was (20.01 ±7.22), which was significantly higher than the former score of (18.79 ± 6.12) (t =2.764,P <0.05).The terminal value of FEV1% was (54.56 ±10.56), which was also significantly lower than the former score of (59.06 ±9.89) (t=-3.038,P<0.05).Conclusions Smoking cessation intervention can relieve the symptoms of patients with chronic airway disease , and delay the decrease of lung function, and improve the patients ’ quality of life.