检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2014年
20期
2822-2823,2827
,共3页
2 型糖尿病%绝经%骨质疏松%亚洲人骨质疏松自我筛查工具
2 型糖尿病%絕經%骨質疏鬆%亞洲人骨質疏鬆自我篩查工具
2 형당뇨병%절경%골질소송%아주인골질소송자아사사공구
type 2 diabetes mellitus%postmenopausal%osteoporosis%Osteoporosis Self-assessment Tool for Asians
目的：评价亚洲人骨质疏松自我筛查工具（OSTA ）指数能否作为骨折风险的初筛指标。方法 Lu-nari 双能 X 线吸收仪测量患者腰椎 L1-4，髋部股骨颈、股骨干、大转子、Ward′s 三角区的骨密度（BMD）值，并按照世界卫生组织推荐的骨质疏松诊断标准将160例患者分为骨质正常组、骨含量减少组与骨质疏松组。比较3组患者的年龄、绝经年限、糖尿病病程等危险因素的差异，及3组患者各部位的 BMD 值及矿盐水平的差异，对3组患者各部位的 BMD 值与 OSTA 指数进行相关性分析，采用受试者工作曲线（ROC）分析 OSTA 指数预测 BMD 值的价值。结果绝经后2型糖尿病（T2DM ）患者骨质疏松组、骨含量减少组、骨含量正常组，在年龄、病程两两间比较差异有统计学意义（P＜0．05）；3组患者在腰椎、股骨颈、Ward′s 区、大转子、股骨干的 BMD 值及矿盐水平，两两比较差异均有统计学意义（P＜0．05）；3组间腰椎、股骨颈、股骨干、Ward′s 三角区的 BMD 值与 OSTA 指数呈正相关关系（P＜0．05）。结论 OSTA 指数作为绝经后 T2DM 患者骨质疏松疾病筛查工具尚需进一步研究。
目的：評價亞洲人骨質疏鬆自我篩查工具（OSTA ）指數能否作為骨摺風險的初篩指標。方法 Lu-nari 雙能 X 線吸收儀測量患者腰椎 L1-4，髖部股骨頸、股骨榦、大轉子、Ward′s 三角區的骨密度（BMD）值，併按照世界衛生組織推薦的骨質疏鬆診斷標準將160例患者分為骨質正常組、骨含量減少組與骨質疏鬆組。比較3組患者的年齡、絕經年限、糖尿病病程等危險因素的差異，及3組患者各部位的 BMD 值及礦鹽水平的差異，對3組患者各部位的 BMD 值與 OSTA 指數進行相關性分析，採用受試者工作麯線（ROC）分析 OSTA 指數預測 BMD 值的價值。結果絕經後2型糖尿病（T2DM ）患者骨質疏鬆組、骨含量減少組、骨含量正常組，在年齡、病程兩兩間比較差異有統計學意義（P＜0．05）；3組患者在腰椎、股骨頸、Ward′s 區、大轉子、股骨榦的 BMD 值及礦鹽水平，兩兩比較差異均有統計學意義（P＜0．05）；3組間腰椎、股骨頸、股骨榦、Ward′s 三角區的 BMD 值與 OSTA 指數呈正相關關繫（P＜0．05）。結論 OSTA 指數作為絕經後 T2DM 患者骨質疏鬆疾病篩查工具尚需進一步研究。
목적：평개아주인골질소송자아사사공구（OSTA ）지수능부작위골절풍험적초사지표。방법 Lu-nari 쌍능 X 선흡수의측량환자요추 L1-4，관부고골경、고골간、대전자、Ward′s 삼각구적골밀도（BMD）치，병안조세계위생조직추천적골질소송진단표준장160례환자분위골질정상조、골함량감소조여골질소송조。비교3조환자적년령、절경년한、당뇨병병정등위험인소적차이，급3조환자각부위적 BMD 치급광염수평적차이，대3조환자각부위적 BMD 치여 OSTA 지수진행상관성분석，채용수시자공작곡선（ROC）분석 OSTA 지수예측 BMD 치적개치。결과절경후2형당뇨병（T2DM ）환자골질소송조、골함량감소조、골함량정상조，재년령、병정량량간비교차이유통계학의의（P＜0．05）；3조환자재요추、고골경、Ward′s 구、대전자、고골간적 BMD 치급광염수평，량량비교차이균유통계학의의（P＜0．05）；3조간요추、고골경、고골간、Ward′s 삼각구적 BMD 치여 OSTA 지수정정상관관계（P＜0．05）。결론 OSTA 지수작위절경후 T2DM 환자골질소송질병사사공구상수진일보연구。
Objective To evaluate the value of Osteoporosis Self-assessment Tool for Asians(OSTA)on post-menopausal osteoporosis in women with type 2 diabetes .Methods A total of 160 postmenopausal women with type 2 diabetes were detected the bone mineral density (BMD)of lumbar L1-4 ,hip femoral neck ,femoral greater trochanter , shaft of femar and Ward′s triangle according to the criteria for diagnosis of osteoporosis recommended by the world health organization .The 160 women were divided into normal bone group ,bone content reduced group and osteoporo-sis group .Risk factors such as age ,postmenopausal time ,course of type 2 diabetes were compared .The BMD of dif-ferent parts of patients′ bodies and the content of bone mineral salt were compared among the three groups .Correla-tion between the BMD and OSTA were analyzed ,and the value of OSTA for predicting the BMD was analyzed by re-ceiver operating characteristic curve(ROC)and regression analysis .Results There were significant differences on the age ,course of disease ,the BMD of different parts of patients′ bodies and the content of bone mineral salt among the three groups(P < 0 .05) .A positive correlation between the BMD and OSTA existed .Conclusion It needs further study that whether OSTA could be used asa predictor of osteoporosis .
