CAJ | 학술논문

目的：探讨间歇重力鼻饲喂养对新生儿重症监护室（ NICU）内极低体重儿胃肠道并发症的影响。方法选取NICU内215例极低体重儿，采用随机数字表法将患儿随机分为观察组106例，对照组109例。观察组采用间歇重力管饲喂养方法，对照组采用持续滴注管饲喂养方法。观察两种鼻饲方法客观指标变化并进行比较。结果观察组和对照组各100例患儿完成研究。观察组极低体重儿转出NICU时体质量增长到（1397．0±22．10）g，高于对照组（1320．0±18．25）g，差异有统计学意义（t＝2．26， P＜0．05）。观察组极低体重儿全胃肠营养所需时间、转出NICU时间为（4．94±0．70），（9．69±7．19）d，均低于对照组[（4．74±0．74），（11．63±4．02）d]，差异均有统计学意义（t值分别为2．72，4．85；P＜0.01）。观察组患儿的腹胀、腹泻、上消化道出血、呕吐发生率均低于对照组，均有统计学意义（ P ＜0.05）；两组患儿均未发生坏死性小肠结肠炎（NEC）。结论应用间歇重力管饲喂养可以减少极低体重儿肠内营养并发症的发生，缩短患儿的NICU入住时间，提高体重增长速度。
목적：탐토간헐중력비사위양대신생인중증감호실（ NICU）내겁저체중인위장도병발증적영향。방법선취NICU내215례겁저체중인，채용수궤수자표법장환인수궤분위관찰조106례，대조조109례。관찰조채용간헐중력관사위양방법，대조조채용지속적주관사위양방법。관찰량충비사방법객관지표변화병진행비교。결과관찰조화대조조각100례환인완성연구。관찰조겁저체중인전출NICU시체질량증장도（1397．0±22．10）g，고우대조조（1320．0±18．25）g，차이유통계학의의（t＝2．26， P＜0．05）。관찰조겁저체중인전위장영양소수시간、전출NICU시간위（4．94±0．70），（9．69±7．19）d，균저우대조조[（4．74±0．74），（11．63±4．02）d]，차이균유통계학의의（t치분별위2．72，4．85；P＜0.01）。관찰조환인적복창、복사、상소화도출혈、구토발생솔균저우대조조，균유통계학의의（ P ＜0.05）；량조환인균미발생배사성소장결장염（NEC）。결론응용간헐중력관사위양가이감소겁저체중인장내영양병발증적발생，축단환인적NICU입주시간，제고체중증장속도。
Objective To evaluate the effects of intermittent nasogastric feeding on neonatal intensive care unit ( NICU) on very low birth weight infants gastrointestinal complications .Methods Two hundred and fifteen very low birth weight infants were randomly assigned to either observation group ( n=106 ) or the control group ( n=109 ) .Infants in the observation group received intermittent gravity tube feeding .Infants in the control group received continuous drip tube feeding .Weight increase , total parenteral nutrition time , length of stay and complication were assessed .Results Observation group of very low birth weight infants when were turned out of the NICU, weight increased to(1 397.0 ±22.10)g, higher than the control group (1 320.0 ± 18.25)g, was statistically significant difference (t=2.26,P<0.05);total parenteral nutrition time, length of stay in NICU were (4.94 ±0.70),(9.69 ±7.19)d,in observation group, were lower than the control group [(4.74 ±0.74),(11.63 ±4.02)d], differences were statistically significant (t=2.72,4.85,respectively;P<0.01).The incidence of abdominal distention , vomiting, diarrhea, upper gastrointestinal bleeding in observation group were lower than the control group , and had statistical significance (P<0.05).However, the very low birth weight infants had not occurred necrotizing enterocolitis in two groups .Conclusions Intermittent nasal tube feeding can reduce the complications of enteral nutrition , shorten the time of hospitalizationand increased body weight growth rate .