CAJ | 학술논문

目的：探讨涎腺腺泡细胞癌(AciCC)的临床病理特征及与生物学行为相关的病理因素。方法：收集1988-2011年，四川大学华西口腔医院的腺泡细胞癌病例68例，进行临床病理学分析和随访调查。结果：平均发病年龄为44.4岁，20岁以下4例（5.9%），男女比例为1∶1.13；就诊平均病程为45.2个月。肿瘤发生于腮腺为57例（83.8%）、腭部为4例（5.9%）、颊部为3例（4.4%）、颌下腺为2例（2.9%)。68例AciCC中，56例获随访信息，随访率为82.4%。复发率为26.5%，颈部淋巴结转移率为8.82%，5年生存率为98.21%。肿瘤间质中有大量淋巴样细胞浸润的患者，复发率较低（P<0.05）。结论：AciCC肿瘤间质中大量淋巴样细胞浸润，是提示患者预后较好的一个病理指标。
목적：탐토연선선포세포암(AciCC)적림상병리특정급여생물학행위상관적병리인소。방법：수집1988-2011년，사천대학화서구강의원적선포세포암병례68례，진행림상병이학분석화수방조사。결과：평균발병년령위44.4세，20세이하4례（5.9%），남녀비례위1∶1.13；취진평균병정위45.2개월。종류발생우시선위57례（83.8%）、악부위4례（5.9%）、협부위3례（4.4%）、합하선위2례（2.9%)。68례AciCC중，56례획수방신식，수방솔위82.4%。복발솔위26.5%，경부림파결전이솔위8.82%，5년생존솔위98.21%。종류간질중유대량림파양세포침윤적환자，복발솔교저（P<0.05）。결론：AciCC종류간질중대량림파양세포침윤，시제시환자예후교호적일개병리지표。
Objective:To discuss the clinico-pathological features of acinic cell carcinoma ( AciCC) and its relation with the biological behavior. Methods:68 cases of acinic cell carcinoma were collected from the files of West China Stomatol-ogy Hospital, Sichuan University. A clinicopathological features and followed up data were analyzed. Results: There were 32 males and 36 tamales with a ratio of 1∶1.13. The mean age of the patients was 44.4 years, 4 of 68 patients (5.9%) were under 20 years old at the time of excision of their primary tumor. The average duration of symptoms was 45.2 months. The majority of AciCC cases located in the parotid gland (57 cases, 83.8%), followed by palate gland (4 cases, 5.9%), buccal gland (3 cases, 4.4%) and submandibular gland (2 cases, 2.9%) respectively. Follow-up information was obtained from 56 cases (82.4%). The local recurrence rate was 26.5%, with a rate of metastasis to cervical lymph nodes in 8.82%. The five year survival rate was 98.21%. In histopathological features, cases those with a prominent lymphoid infiltration of the stro-ma had a more favorable prognosis, and with a lower recurrence rate (P<0.05). Conclusion: A prominent lymphoid infil-trate of the stroma is a valuable pathological parameter predicting a favorable prognosis of AciCC.