国际妇产科学杂志
國際婦產科學雜誌
국제부산과학잡지
JOURNAL OF INTERNATIONAL OBSTETRICS AND GYNECOLOGY
2014年
5期
531-533
,共3页
朱定军%张蔚%吕琼莹%张娟%李菲%郑文静
硃定軍%張蔚%呂瓊瑩%張娟%李菲%鄭文靜
주정군%장위%려경형%장연%리비%정문정
宫颈肿瘤%腹腔镜%子宫颈%子宫切除术%妊娠结局
宮頸腫瘤%腹腔鏡%子宮頸%子宮切除術%妊娠結跼
궁경종류%복강경%자궁경%자궁절제술%임신결국
Uterine cervical neoplasms%Laparoscopes%Cervix uteri%Hysterectomy%Pregnancy outcome
目的:评估早期年轻宫颈癌患者在腹腔镜下保留生育功能的根治性宫颈切除术(LRT)后的妊娠结局。方法:回顾性分析2006年4月-2013年12月武汉大学人民医院收治的早期宫颈癌患者行LRT的临床资料,妊娠结局的数据从患者的病历记录和电话回访中获得。结果:纳入22例成功行LRT的患者,中位年龄32岁(22~40岁),LRT后的平均随访时间是28个月(3~82个月)。手术后所有患者均恢复月经,其中20例月经规律(90.9%),2例月经不规律(9.1%)。5例患者出现宫颈管狭窄(22.7%),主要表现为月经规律但经量减少,出现痛经。些患者采取了宫颈管扩张术。12例患者在术后试图妊娠,其中7例妊娠了11次(其中3次流产,6次早产和2次足月产)。12例患者中的7例生产了6例健康婴儿。LRT术后的妊娠率是58.3%(7/12)。自然流产率和活产率分别是27.3%(3/11)和72.7%(8/11),早产率是54.5%(6/11)。结论:LRT术后患者的妊娠率和活产率是很有前途的;然而其早产率也明显增高;宫颈狭窄发生比例较低。
目的:評估早期年輕宮頸癌患者在腹腔鏡下保留生育功能的根治性宮頸切除術(LRT)後的妊娠結跼。方法:迴顧性分析2006年4月-2013年12月武漢大學人民醫院收治的早期宮頸癌患者行LRT的臨床資料,妊娠結跼的數據從患者的病歷記錄和電話迴訪中穫得。結果:納入22例成功行LRT的患者,中位年齡32歲(22~40歲),LRT後的平均隨訪時間是28箇月(3~82箇月)。手術後所有患者均恢複月經,其中20例月經規律(90.9%),2例月經不規律(9.1%)。5例患者齣現宮頸管狹窄(22.7%),主要錶現為月經規律但經量減少,齣現痛經。些患者採取瞭宮頸管擴張術。12例患者在術後試圖妊娠,其中7例妊娠瞭11次(其中3次流產,6次早產和2次足月產)。12例患者中的7例生產瞭6例健康嬰兒。LRT術後的妊娠率是58.3%(7/12)。自然流產率和活產率分彆是27.3%(3/11)和72.7%(8/11),早產率是54.5%(6/11)。結論:LRT術後患者的妊娠率和活產率是很有前途的;然而其早產率也明顯增高;宮頸狹窄髮生比例較低。
목적:평고조기년경궁경암환자재복강경하보류생육공능적근치성궁경절제술(LRT)후적임신결국。방법:회고성분석2006년4월-2013년12월무한대학인민의원수치적조기궁경암환자행LRT적림상자료,임신결국적수거종환자적병력기록화전화회방중획득。결과:납입22례성공행LRT적환자,중위년령32세(22~40세),LRT후적평균수방시간시28개월(3~82개월)。수술후소유환자균회복월경,기중20례월경규률(90.9%),2례월경불규률(9.1%)。5례환자출현궁경관협착(22.7%),주요표현위월경규률단경량감소,출현통경。사환자채취료궁경관확장술。12례환자재술후시도임신,기중7례임신료11차(기중3차유산,6차조산화2차족월산)。12례환자중적7례생산료6례건강영인。LRT술후적임신솔시58.3%(7/12)。자연유산솔화활산솔분별시27.3%(3/11)화72.7%(8/11),조산솔시54.5%(6/11)。결론:LRT술후환자적임신솔화활산솔시흔유전도적;연이기조산솔야명현증고;궁경협착발생비례교저。
Objective: The objective of this study was to estimate the reproductive outcome of young women with early-stage cervical cancer who underwent fertility-sparing laparoscopic radical trachelectomy (LRT). Methods:We performed a retrospective review of the medical records of patients with early-stage cervical cancer who underwent LRT from April 2006 to December 2013. Clinicopathological data were obtained from patient medical records ,and reproductive outcome data were obtained from patient medical records and telephone interviews. Results:Twenty-two patients who underwent successful LRT were included in this study. The median age of patients was 32 years(range,22 to 40 years),and the median follow-up time after LRT was 28 months (range,3 to 82 months). Menstruation resumed in all patients after LRT,with twenty patients (90.9%) and two patients (9.1%) reporting regular and irregular menstruation,respectively. Five patients(22.7%) presented with cervical stenosis,which was manifested by regular but decreased menstrual flow and newly-developed dysmenorrhea. These patients underwent cervical cannulation and dilatation. Eleven pregnancies (including 3 missed abortions,6 preterm births and 2 full-term births) occurred in 7 patients after LRT. Seven out of 12 patients gave birth to 6 healthy babies. The pregnancy rate after LRT was 58.3%(7/12). The spontaneous abortion rate and live birth rate were 27.3%(3/11) and 72.7%(8/11),respectively. The preterm birth rate was 54.5%(6/11). Conclusions:Pregnancy and live birth rates after LRT were promising; however,the preterm birth rate was relatively high. Cervical stenosis also occurred in a small percentage of patients.