西北药学杂志
西北藥學雜誌
서북약학잡지
2014年
6期
634-636
,共3页
原发性高血压%拉贝洛尔%Meta 分析
原髮性高血壓%拉貝洛爾%Meta 分析
원발성고혈압%랍패락이%Meta 분석
essential hypertension%labetalol%Meta analysis
目的:利用 Meta 分析方法评价拉贝洛尔对高血压急症的疗效与安全性,为临床安全合理用药提供参考。方法以拉贝洛尔、高血压急症为关键词,计算机检索中国数据库,按纳入标准选取拉贝洛尔治疗高血压急症的随机对照试验,用 Meta 分析方法,运用 Rev Man 5.2软件对纳入文献进行分析。结果共纳入5篇文献,Meta 结果显示,拉贝洛尔与对照降压药的不良反应也没有明显差异。结论拉贝洛尔对高血压急症患者有明显的降压作用,降压效果和不良反应与对照降压药基本相同。
目的:利用 Meta 分析方法評價拉貝洛爾對高血壓急癥的療效與安全性,為臨床安全閤理用藥提供參攷。方法以拉貝洛爾、高血壓急癥為關鍵詞,計算機檢索中國數據庫,按納入標準選取拉貝洛爾治療高血壓急癥的隨機對照試驗,用 Meta 分析方法,運用 Rev Man 5.2軟件對納入文獻進行分析。結果共納入5篇文獻,Meta 結果顯示,拉貝洛爾與對照降壓藥的不良反應也沒有明顯差異。結論拉貝洛爾對高血壓急癥患者有明顯的降壓作用,降壓效果和不良反應與對照降壓藥基本相同。
목적:이용 Meta 분석방법평개랍패락이대고혈압급증적료효여안전성,위림상안전합리용약제공삼고。방법이랍패락이、고혈압급증위관건사,계산궤검색중국수거고,안납입표준선취랍패락이치료고혈압급증적수궤대조시험,용 Meta 분석방법,운용 Rev Man 5.2연건대납입문헌진행분석。결과공납입5편문헌,Meta 결과현시,랍패락이여대조강압약적불량반응야몰유명현차이。결론랍패락이대고혈압급증환자유명현적강압작용,강압효과화불량반응여대조강압약기본상동。
Objective This paper used Meta analysis method to evaluate the effect and safety of labetalol to hypertensive emergency and to provide reference for rational and safe drug application .Methods By using labetalol and hypertensive emergency as key words ,and according to the inclusion criteria selection ,labetalol randomized controlled trials for the treatment of hypertensive e-mergency in China′s database ,were rearched and analyzed with Rev Man 5 .2 software .Results Total of 5 articles ,according to the results of Meta ,showed no obvious different adverse reactions between labetalol and contrast antihypertensive drugs .Conclu-sion That labetalol has obvious function in patients with hypertensive emergency .The antihypertensive effects and adverse reac-tions compared with the contrast antihypertensive drugs are basically the same .