CAJ | 학술논문

目的：探讨血浆 D-二聚体（D-dimer，DD）和纤维蛋白原降解产物（fibrinogen degradation products，FDP）在过敏性紫癜（HSP）患者中的早期诊断价值。方法选取本院2013年1月～2014年2月过敏性紫癜患者53例作为研究组，同期本院健康体检者共30例为对照组，分别测定两组血浆 D-二聚体和纤维蛋白原降解产物的变化情况。结果 HSP 组 D-二聚体和 FDP 水平显著高于对照组，差异有统计学意义（P ＜0.05）。结论 D-二聚体和 FDP 联合检测有助于早期判断过敏性紫癜的严重程度及疗效观察。
목적：탐토혈장 D-이취체（D-dimer，DD）화섬유단백원강해산물（fibrinogen degradation products，FDP）재과민성자전（HSP）환자중적조기진단개치。방법선취본원2013년1월～2014년2월과민성자전환자53례작위연구조，동기본원건강체검자공30례위대조조，분별측정량조혈장 D-이취체화섬유단백원강해산물적변화정황。결과 HSP 조 D-이취체화 FDP 수평현저고우대조조，차이유통계학의의（P ＜0.05）。결론 D-이취체화 FDP 연합검측유조우조기판단과민성자전적엄중정도급료효관찰。
Objective To discuss the early diagnostic value of acute-phase D-dimer and fibrinogen degradation products (FDP) in pations with Henoch-schonlein purpura (HSP) . Methods Blood samples were collected from 53 acute HSP people from January 2013 to February 2014 and 30 healthy as the control group. FDP and D-dimer were detected to know the changes in them. Results Compared with the control group ,the patients had the significantly high level of D-dimer and FDP. There was significant difference in D-dimer and FDP between 2 groups (P<0.05) Conclusion Joint detection is contributive to the early judgement of patient acuity and effect observation.