CAJ | 학술논문

目的：探讨低温可调钠血液透析联合左卡尼汀治疗对维持性透析低血压的临床疗效。方法随机选择我院收治的维持性血液透析低血压患者68例，对照组先接受常规血液透析6个月，观察组给予使用低温可调钠血液透析联合左卡尼汀进行治疗。比较两组低血压事件发生率、动脉压平均水平、血清钠浓度、C 反应蛋白水平、心血管事件发生率以及内瘘闭塞发生率。结果观察组并发症及低血压发生概率明显低于对照组，P ＜0.05，透析后 MAP 水平及 C 蛋白反应优于对照组，P ＜0.05，透析后血清钠浓度及尿素氮清除率无明显差异，P ＞0.05。结论低温可调钠血液透析联合左卡尼汀治疗对维持性透析低血压的效果显著。、
목적：탐토저온가조납혈액투석연합좌잡니정치료대유지성투석저혈압적림상료효。방법수궤선택아원수치적유지성혈액투석저혈압환자68례，대조조선접수상규혈액투석6개월，관찰조급여사용저온가조납혈액투석연합좌잡니정진행치료。비교량조저혈압사건발생솔、동맥압평균수평、혈청납농도、C 반응단백수평、심혈관사건발생솔이급내루폐새발생솔。결과관찰조병발증급저혈압발생개솔명현저우대조조，P ＜0.05，투석후 MAP 수평급 C 단백반응우우대조조，P ＜0.05，투석후혈청납농도급뇨소담청제솔무명현차이，P ＞0.05。결론저온가조납혈액투석연합좌잡니정치료대유지성투석저혈압적효과현저。、
Objective To explore the clinical effect on maintenance dialysis hypotension by adjustable sodium hemodialysis under low temperature combined with l-carnitine therapy. Method 68 patients with maintenance hemodialysis hypotension received in our hospital were selected at random with six-month conventional hemodialysis given to control group, while the observation group adopted the treatment combined with adjustable sodium hemodialysis under low temperature and l-carnitine treatment. The incidence of hypotension accidents, cardiovascular accidents, fistula occlusion as well as the average level of arterial pressure, concentration of serum sodium and level of C-reaction protein of patients in the two groups were compared. Result Complications as well as incidence of hypotension in observation group were obviously lower than that in control group with P<0.05, and the MAP level as well as C-reactive protein after the hemodialysis were better than the control group with P<0.05, while there were obvious differences after the hemodialysis regarding serum sodium concentration as well as removal rate of urea nitrogen with P>0.05. Conclusion It has significant effect on treating maintenance hemodialysis hypotension to combine adjustable sodium hemodialysis under low temperature with l-carnitine.