CAJ | 학술논문

目的：探讨妊娠急性脂肪肝早期诊断方法和治疗。方法选取我院2011年12月～2012年12月接收的4例妊娠期急性脂肪肝患者为观察对象，对临床资料进行回顾性分析。结果患者临床表现有：恶心、呕吐、浑身无力、厌食和黄疸等；经实验室检查患者有肝功能异常、门冬氨酸氨基转移酶及丙氨酸氨基转移酶都有轻度或者中度的表现，胆红素和直接胆红素升高，白蛋白降低，患者肾功能异常，肌酐和尿素氨升高，患者的凝血酶原时间延长，血小板减少。4例患者中1例死亡，新生儿全部成活。结论及早诊断并及时终止妊娠，给予患者支持疗法是治疗妊娠急性脂肪肝的关键，能够降低孕妇及新生儿的死亡率。
목적：탐토임신급성지방간조기진단방법화치료。방법선취아원2011년12월～2012년12월접수적4례임신기급성지방간환자위관찰대상，대림상자료진행회고성분석。결과환자림상표현유：악심、구토、혼신무력、염식화황달등；경실험실검사환자유간공능이상、문동안산안기전이매급병안산안기전이매도유경도혹자중도적표현，담홍소화직접담홍소승고，백단백강저，환자신공능이상，기항화뇨소안승고，환자적응혈매원시간연장，혈소판감소。4례환자중1례사망，신생인전부성활。결론급조진단병급시종지임신，급여환자지지요법시치료임신급성지방간적관건，능구강저잉부급신생인적사망솔。
Objective To explore the diagnosis and treatment for acute fatty liver in an early stage during pregnancy. Method 4 patients with acute fatty liver during pregnancy received in our hospital from December 2011 to December 2012 were selected as observation objectives with retrospective analysis on clinical materials. Result Clinical manifestations of the patients were nausea, sickness, weakness, anorexia, icterus and so on. Patients were tested with abnormal liver functions, high bilirubin and direct bilirubin, low albumin, abnormal renal function, high creatinine and urea ammonia, longer prothrombin, and less blood platelet. Among the four patients, one died but all newborns survived. Conclusion Supportive therapy is the key to treat acute fatty liver during pregnancy with earlier diagnosis as well as timely termination of pregnancy, which can reduce the mortality rate of pregnant as well as newborns.