中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2014年
10期
1328-1329
,共2页
中老年%呼吸道感染%甘露聚糖肽
中老年%呼吸道感染%甘露聚糖肽
중노년%호흡도감염%감로취당태
Elders%Respiratory tract infections%Mannatide
目的：观察甘露聚糖肽口服液用于防治中老年人反复发作的呼吸道感染的临床疗效。方法：96例反复发生呼吸道感染的中老年患者，按随机数字表法进行随机分组，分别为对照组和治疗组，治疗组患者给予抗感染及对症治疗基础上服用甘露聚糖肽口服液，对照组患者给予抗感染及对症治疗基础上服用匹多莫德口服液，连用8周。结果：两组比较临床疗效无统计学差异(P＞0.05)，但在临床主症和体征消失所需时间和抗生素用量方面，治疗组优势较为显著(P＜0.05)。随访1年治疗组患者感染复发次数较对照组显著降低(P＜0.05)。治疗结束时，治疗组患者血清IgG、IgA、IgM水平较对照组升高更为显著(P＜0.05)，并且两组中性粒细胞比例比较差异具有统计学意义(P＜0.05)。结论：甘露聚糖肽口服液能增强反复呼吸道感染中老年患者免疫功能，缩短临床主症治愈时间，降低呼吸道感染发病率。
目的：觀察甘露聚糖肽口服液用于防治中老年人反複髮作的呼吸道感染的臨床療效。方法：96例反複髮生呼吸道感染的中老年患者，按隨機數字錶法進行隨機分組，分彆為對照組和治療組，治療組患者給予抗感染及對癥治療基礎上服用甘露聚糖肽口服液，對照組患者給予抗感染及對癥治療基礎上服用匹多莫德口服液，連用8週。結果：兩組比較臨床療效無統計學差異(P＞0.05)，但在臨床主癥和體徵消失所需時間和抗生素用量方麵，治療組優勢較為顯著(P＜0.05)。隨訪1年治療組患者感染複髮次數較對照組顯著降低(P＜0.05)。治療結束時，治療組患者血清IgG、IgA、IgM水平較對照組升高更為顯著(P＜0.05)，併且兩組中性粒細胞比例比較差異具有統計學意義(P＜0.05)。結論：甘露聚糖肽口服液能增彊反複呼吸道感染中老年患者免疫功能，縮短臨床主癥治愈時間，降低呼吸道感染髮病率。
목적：관찰감로취당태구복액용우방치중노년인반복발작적호흡도감염적림상료효。방법：96례반복발생호흡도감염적중노년환자，안수궤수자표법진행수궤분조，분별위대조조화치료조，치료조환자급여항감염급대증치료기출상복용감로취당태구복액，대조조환자급여항감염급대증치료기출상복용필다막덕구복액，련용8주。결과：량조비교림상료효무통계학차이(P＞0.05)，단재림상주증화체정소실소수시간화항생소용량방면，치료조우세교위현저(P＜0.05)。수방1년치료조환자감염복발차수교대조조현저강저(P＜0.05)。치료결속시，치료조환자혈청IgG、IgA、IgM수평교대조조승고경위현저(P＜0.05)，병차량조중성립세포비례비교차이구유통계학의의(P＜0.05)。결론：감로취당태구복액능증강반복호흡도감염중노년환자면역공능，축단림상주증치유시간，강저호흡도감염발병솔。
Objective: To observe the clinical efifcacy of mannatide to treat elder patients with recurrent respiratory tract infection. Methods:96 cases of elder patients with recurrent respiratory tract infection were divided into control and treatment groups by the random table number.Based on the anti-infective and symptomatic treatment, the treatment group was added Mannatide oral liquid, and the control group was added pidotimod oral liquid, applied for 8 weeks.Results:Compared to the control group, the clinical efifcacy of the two groups showed no signiifcant difference (P>0.05), while the disappearing time of main clinical symptoms and signs, and the usage of antibiotics in the treatment group were significantly more advantages (P<0.05).The relapse number of recurrent infections of treatment group was signiifcantly lower than the control group 1-year follow-up after treatment (P<0.05). At the end of treatment, serum IgG, IgA, IgM levels of patients in treatment group increased more signiifcantly than control group (P<0.05), and the proportion of neutrophils of two groups showed statistically signiifcant difference(P<0.05).Conclusion:Mannatide oral liquid can enhance immune function in elderly patients with recurrent respiratory tract infection, shorten healing time of main clinical symptoms, and reduce the incidence of respiratory tract infections.
