中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2014年
10期
1300-1301,1304
,共3页
炎症表型%哮喘%临床特征
炎癥錶型%哮喘%臨床特徵
염증표형%효천%림상특정
Inflammatory phenotype%Asthma%Clinical features
目的:对比研究不同炎症表型支气管哮喘患者的临床特征,为临床诊治提供合理建议。方法:选取2010~2012年哮喘患者302例,依据诱导痰炎症细胞分类结果对患者进行分组,对不同组别患者的进行研究。结果:不同炎症表型哮喘患者的病情、呼吸道感染、白细胞比较、BMI、静脉血Eos数目比较,差异有统计学意义(P<0.05);混合细胞性哮喘患者的诱导痰炎症细胞总数高于其他类型患者;不同炎症表型哮喘患者治疗前肺功能比较,除FEV1%预计值外,其他指标比较,差异均无统计学意义(P>0.05)。结论:哮喘患者存在不同的炎症表型,但其临床特征差异并不大。
目的:對比研究不同炎癥錶型支氣管哮喘患者的臨床特徵,為臨床診治提供閤理建議。方法:選取2010~2012年哮喘患者302例,依據誘導痰炎癥細胞分類結果對患者進行分組,對不同組彆患者的進行研究。結果:不同炎癥錶型哮喘患者的病情、呼吸道感染、白細胞比較、BMI、靜脈血Eos數目比較,差異有統計學意義(P<0.05);混閤細胞性哮喘患者的誘導痰炎癥細胞總數高于其他類型患者;不同炎癥錶型哮喘患者治療前肺功能比較,除FEV1%預計值外,其他指標比較,差異均無統計學意義(P>0.05)。結論:哮喘患者存在不同的炎癥錶型,但其臨床特徵差異併不大。
목적:대비연구불동염증표형지기관효천환자적림상특정,위림상진치제공합리건의。방법:선취2010~2012년효천환자302례,의거유도담염증세포분류결과대환자진행분조,대불동조별환자적진행연구。결과:불동염증표형효천환자적병정、호흡도감염、백세포비교、BMI、정맥혈Eos수목비교,차이유통계학의의(P<0.05);혼합세포성효천환자적유도담염증세포총수고우기타류형환자;불동염증표형효천환자치료전폐공능비교,제FEV1%예계치외,기타지표비교,차이균무통계학의의(P>0.05)。결론:효천환자존재불동적염증표형,단기림상특정차이병불대。
Objective: To compare the different clinical features of inlfammatory phenotypes in asthma patients for clinical diagnosis and treatment to provide reasonable suggestions.Methods:302 cases of asthma were selected in our hospital from January 2010 to December 2012,the Patients were divided into different group according to the sputum inlfammatory cells classiifcation results,the patients of different groups were studied.Results:The asthma,respiratory infection,white blood cells of different inflammatory disease phenotype,BMI,the number of blood Eos in patients,the difference was statistically signiifcant (P<0.05);The total number of inlfammatory cells in hybrid cell asthma patients were more than other type patients;The lung function of different phenotypes asthma inlfammation before treatment were compared,except FEV1% predicted value addition,other indicators,the difference was not statistically signiifcant (P>0.05).Conclusion:The inlfammatory asthma phenotypes existence of different,but their clinical features is not much difference.