浙江化工
浙江化工
절강화공
ZHEJIANG CHEMICAL INDUSTRY
2014年
10期
23-27
,共5页
异香豆素%CuI%微波辐射%偶联反应
異香豆素%CuI%微波輻射%偶聯反應
이향두소%CuI%미파복사%우련반응
isocoumarins%CuI%microwave radiation%coupling reaction
在微波辐射条件下，用CuI催化邻卤代苯甲酸与1,3-二酮类化合物进行偶联反应，合成了7个异香豆素类衍生物，产率为59.5%~81.3%，其结构经1HNMR，13CNMR和MS表征确认。与传统方法比较，具有操作简单、反应时间短的优点。
在微波輻射條件下，用CuI催化鄰滷代苯甲痠與1,3-二酮類化閤物進行偶聯反應，閤成瞭7箇異香豆素類衍生物，產率為59.5%~81.3%，其結構經1HNMR，13CNMR和MS錶徵確認。與傳統方法比較，具有操作簡單、反應時間短的優點。
재미파복사조건하，용CuI최화린서대분갑산여1,3-이동류화합물진행우련반응，합성료7개이향두소류연생물，산솔위59.5%~81.3%，기결구경1HNMR，13CNMR화MS표정학인。여전통방법비교，구유조작간단、반응시간단적우점。
Seven different isocoumarin derivatives were synthesized from o-halobenzoic acids and 1,3-diketones derivatives catalyzed by CuI under microwave radiation with yields of 59.5%~81.3%. The struc-tures of isocoumarin derivatives were confirmed by 1HNMR, 13CNMR and MS confirmation. Compared with traditional methods, this method has the merits of simple operation and short reaction time.
