CAJ | 학술논문

目的：探讨膀胱肿瘤抗原（BTAstat）和透明质酸（HA）在膀胱肿瘤诊断中的应用价值。方法选择2012年5月-2013年5月在我院接受治疗的膀胱肿瘤患者40例，检测清洁中段晨尿中的 BTAstat、HA指标，计算 BT-Astat、HA与BTAstat＋HA指标的敏感度和特异度，分析BTAstat、HA指标敏感度与膀胱肿瘤临床病理的关系，以及检测耗时、费用等可行性指标，评价其临床应用价值。结果 BTAstat＋HA指标对膀胱肿瘤的敏感度最高，明显高于 HA、BTAstat单项指标，差异具有统计学意义（P＜0．05）。BTAstat、HA指标的敏感度随着膀胱肿瘤的分级、分期逐渐升高而升高，且多发肿瘤的敏感度明显高于单发肿瘤，初发肿瘤的敏感度高于复发肿瘤。结论 BTAstat＋HA检测对膀胱肿瘤的诊断敏感度高，具有重要的应用价值，可以促进明确诊断，且可重复性、易操作性强，费用合理，值得临床应用。
목적：탐토방광종류항원（BTAstat）화투명질산（HA）재방광종류진단중적응용개치。방법선택2012년5월-2013년5월재아원접수치료적방광종류환자40례，검측청길중단신뇨중적 BTAstat、HA지표，계산 BT-Astat、HA여BTAstat＋HA지표적민감도화특이도，분석BTAstat、HA지표민감도여방광종류림상병리적관계，이급검측모시、비용등가행성지표，평개기림상응용개치。결과 BTAstat＋HA지표대방광종류적민감도최고，명현고우 HA、BTAstat단항지표，차이구유통계학의의（P＜0．05）。BTAstat、HA지표적민감도수착방광종류적분급、분기축점승고이승고，차다발종류적민감도명현고우단발종류，초발종류적민감도고우복발종류。결론 BTAstat＋HA검측대방광종류적진단민감도고，구유중요적응용개치，가이촉진명학진단，차가중복성、역조작성강，비용합리，치득림상응용。
Objective To discuss the value of bladder tumor antigen (BTAstat)and hyaluronic acid (HA)in the di-agnosis of bladder tumor.Methods 40 cases with bladder tumor treatment from May 2012 to May 2013 in our hospi-tal.BTAstat,HA index of cleaning midpiece urine was detected,the sensitivity and specificityof BTAstat,HA and BT-Astat+ HA index were calculated,and the relationship between BTAstat,HA sensitivity index and bladder tumor clin-ical pathological,time-consuming,cost feasibility index were analyzed to evaluate its clinical application value.Results The BTA Stat+HA index of bladder tumor was the highest sensitivity,significantly higher than HA,BTAstat single index,with significant difference (P<0.05).BTAstat,the HA index of sensitivity with the grading,staging of bladder tumors gradually increased,and multiple tumor was more sensitive than single tumor,primary tumor sensitivity is high-er than that of tumor recurrence.Conclusion BTA StatHA has important application value in the diagnosis of bladder tumor,can promote the diagnosis,its sensitivity is high,and detecting the presence of repeatability and easy to opera-tion,reasonable cost,and is worthy of clinical application.