中国医疗设备
中國醫療設備
중국의료설비
CHINA MEDICAL EQUIPMENT
2014年
10期
156-158
,共3页
双源CT容积灌注成像技术%孤立性肺结节%血容量%血流量%表面通透性
雙源CT容積灌註成像技術%孤立性肺結節%血容量%血流量%錶麵通透性
쌍원CT용적관주성상기술%고립성폐결절%혈용량%혈류량%표면통투성
dual-source CT volume perfusion imaging technology%solitary pulmonary nodule%blood volume%blood lfow%permeability surface
目的：探讨双源CT容积灌注成像技术在诊断孤立性肺结节（SPN）中的应用价值。方法选取2011年3月~2013年12月我院经病理确诊的116例SPN患者，均行双源CT容积灌注成像扫描，观察CT图像特征，并分析血容量（BV）、血流量（BF）、表面通透性（PS）、对比剂平均通过时间（MTT）等，计算可测层面的SPN平均灌注值。根据病理诊断结果进行SPN的良、恶性分组。结果恶性结节的BV、BF和PS值分别为（4.63±1.52）mL/100g、（98.36±48.25）mL/（100g·min）和（17.23±7.65）mL/（100g·min），均显著高于良性结节病例值（2.28±1.76）mL/100g、（46.33±30.23）mL/（100g·min）和（7.42±7.28）mL/（100g·min），差异具有统计学意义（P<0.05）；恶性结节和良性结节的MTT值分别为（5.13±2.52）s、（6.16±4.88）s，差异无统计学意义（P>0.05）。单独利用BV、BF或PS诊断SPN良、恶性的敏感性分别为95%、91%、86%；单独利用BV、BF或PS诊断SPN良、恶性的特异性分别68%、64%、77%。BV+PS及BF+PS联合诊断SPN良、恶性的特异性均为82%，较应用单个指标的特异性增高。结论采用双源CT容积灌注技术诊断和鉴别SPN可提高检出率，可为早期确诊提供证据。
目的：探討雙源CT容積灌註成像技術在診斷孤立性肺結節（SPN）中的應用價值。方法選取2011年3月~2013年12月我院經病理確診的116例SPN患者，均行雙源CT容積灌註成像掃描，觀察CT圖像特徵，併分析血容量（BV）、血流量（BF）、錶麵通透性（PS）、對比劑平均通過時間（MTT）等，計算可測層麵的SPN平均灌註值。根據病理診斷結果進行SPN的良、噁性分組。結果噁性結節的BV、BF和PS值分彆為（4.63±1.52）mL/100g、（98.36±48.25）mL/（100g·min）和（17.23±7.65）mL/（100g·min），均顯著高于良性結節病例值（2.28±1.76）mL/100g、（46.33±30.23）mL/（100g·min）和（7.42±7.28）mL/（100g·min），差異具有統計學意義（P<0.05）；噁性結節和良性結節的MTT值分彆為（5.13±2.52）s、（6.16±4.88）s，差異無統計學意義（P>0.05）。單獨利用BV、BF或PS診斷SPN良、噁性的敏感性分彆為95%、91%、86%；單獨利用BV、BF或PS診斷SPN良、噁性的特異性分彆68%、64%、77%。BV+PS及BF+PS聯閤診斷SPN良、噁性的特異性均為82%，較應用單箇指標的特異性增高。結論採用雙源CT容積灌註技術診斷和鑒彆SPN可提高檢齣率，可為早期確診提供證據。
목적：탐토쌍원CT용적관주성상기술재진단고립성폐결절（SPN）중적응용개치。방법선취2011년3월~2013년12월아원경병리학진적116례SPN환자，균행쌍원CT용적관주성상소묘，관찰CT도상특정，병분석혈용량（BV）、혈류량（BF）、표면통투성（PS）、대비제평균통과시간（MTT）등，계산가측층면적SPN평균관주치。근거병리진단결과진행SPN적량、악성분조。결과악성결절적BV、BF화PS치분별위（4.63±1.52）mL/100g、（98.36±48.25）mL/（100g·min）화（17.23±7.65）mL/（100g·min），균현저고우량성결절병례치（2.28±1.76）mL/100g、（46.33±30.23）mL/（100g·min）화（7.42±7.28）mL/（100g·min），차이구유통계학의의（P<0.05）；악성결절화량성결절적MTT치분별위（5.13±2.52）s、（6.16±4.88）s，차이무통계학의의（P>0.05）。단독이용BV、BF혹PS진단SPN량、악성적민감성분별위95%、91%、86%；단독이용BV、BF혹PS진단SPN량、악성적특이성분별68%、64%、77%。BV+PS급BF+PS연합진단SPN량、악성적특이성균위82%，교응용단개지표적특이성증고。결론채용쌍원CT용적관주기술진단화감별SPN가제고검출솔，가위조기학진제공증거。
Objective To explore the application value of Dual-source CT volume perfusion imaging in the diagnosis of solitary pulmonary nodules (SPNs). Methods 116 cases of SPNs confirmed by pathological diagnosis in our hospital from March 2011 to December 2013 were chosen. All the patients were examined by Dual-source CT perfusion scans, and then we observed the characteristics of CT imaging and analyzed the blood volume (BV), blood lfow (BF), permeability surface (PS), mean transit time (MTT) to calculate average perfusion values of SPNs’ measurable layer. Benign and malignant groups were divided according to the results of pathological diagnosis. Results The values of BV, BF and PS in malignant group were (4.63±1.52) mL/100g, (98.36±48.25) mL/(100g?min) and (17.23±7.65) mL/(100g?min) respectively, and these values were obviously higher than those of benign group, whose values were (2.28±1.76) mL/100g, (46.33±30.23) mL/(100g?min) and (7.42±7.28) mL/(100g?min), respectively. There were signiifcant differences in BV, BF and PS values between malignant group and benign group (P<0.05). The values of MTT in benign group and malignant group were (5.13±2.52) s and (6.16±4.88) s, respectively, and the differences in MTT values between two groups were not signiifcant (P>0.05). In diagnosing benign and malignant SPNs, the diagnosis sensitivities based solely on BV, BF or PS were 95%, 91%and 86%, respectively and the specificities were 68%, 64%and 77%, respectively. The diagnosis sensitivities of BV+PS and BF+PS were both 82%, which is higher than that of using a single indicator. Conclusion The application of Dual-source CT volume perfusion technology can improve the detection rate of SPNs and provide evidences for early conifrmation of SPN.
