CAJ | 학술논문

目的：探讨病证结合优化方案治疗支气管哮喘的临床疗效。方法选择江苏省中西医结合医院2011年1月-2014年1月门诊及住院支气管哮喘患者72例，根据治疗方案分为中药组26例，西药组20例，中西医结合组26例。中药组患者采用病证结合优化方案，西药组患者吸入沙美特罗替卡松，中西医结合组患者联合应用中药组和西药组治疗方案。3组患者均连续治疗10 d，为1个疗程。观察3组患者临床疗效、治疗前后 FEV1及治疗期间不良反应情况。结果中药组、西药组、中西医结合组均未出现无效患者，总有效率均为100%（P >0.05）。3组患者治疗前后FEV1比较，差异均无统计学意义（P >0.05），各组治疗后 FEV1均高于治疗前（P <0.05）。治疗期间，西药组患者出现心悸2例，中西医结合组出现咽喉炎1例，中药组患者未出现明显不良反应。结论单纯中药治疗、单纯西药治疗及病证结合优化方案治疗支气管哮喘临床疗效相当，均可有效改善患者 FEV1，且不良反应较少，安全性较高。
목적：탐토병증결합우화방안치료지기관효천적림상료효。방법선택강소성중서의결합의원2011년1월-2014년1월문진급주원지기관효천환자72례，근거치료방안분위중약조26례，서약조20례，중서의결합조26례。중약조환자채용병증결합우화방안，서약조환자흡입사미특라체잡송，중서의결합조환자연합응용중약조화서약조치료방안。3조환자균련속치료10 d，위1개료정。관찰3조환자림상료효、치료전후 FEV1급치료기간불량반응정황。결과중약조、서약조、중서의결합조균미출현무효환자，총유효솔균위100%（P >0.05）。3조환자치료전후FEV1비교，차이균무통계학의의（P >0.05），각조치료후 FEV1균고우치료전（P <0.05）。치료기간，서약조환자출현심계2례，중서의결합조출현인후염1례，중약조환자미출현명현불량반응。결론단순중약치료、단순서약치료급병증결합우화방안치료지기관효천림상료효상당，균가유효개선환자 FEV1，차불량반응교소，안전성교고。
Objective To investigate the effect of optimum proposal of integration of disease and TCM syndrome on bronchial asthma. Methods Seventy - two patients with bronchial asthma admitted to our hospital from January 2011 to January 2014 were chosen,and then they were randomly divided into Chinese herbal group(n = 26),western medicine group(n = 20) and combination group(n = 26). Chinese herbal group was treated with optimum proposal of integration of disease and TCM syn-drome,western medicine group was treated with salmeterol flutieasone inhalation,while combination group was treated with opti-mum proposal of integration of disease and TCM syndrome and salmeterol flutieasone inhalation. All groups treated for 10 days. Clinical effect,FEV1 before and after treatment,adverse reactions during treatment were observed in the three groups. Re-sults There was no invalid patients in the three groups,all of the total effective rate of the three groups was 100% (P > 0. 05). There was no significant differences of FEV1 in the three groups before and after treatment(P > 0. 05),while FEV1 after treat-ment was higher than before in each group( P < 0. 05). During treatment,2 cases occurred palpitation in western medicine group,1 case occurred sphagitis in combination group,no one occurred adverse reactions in Chinese herbal group. Conclusion Simple Chinese herbal therapy,simple western medicine therapy and optimum proposal of integration of disease and TCM syn-drome have similar effect on bronchial asthma,they all can improve FEV1 ,are safe.