CAJ | 학술논문

目的：探讨产前超声筛查对妊娠中期胎儿复杂先天性心脏畸形的诊断价值。方法回顾性分析2012年2月-2014年2月在我院进行产前超声筛查的9300例妊娠中期孕妇的超声检查资料，比较超声检查结果和产后随访结果。结果9300例孕妇共检出27例复杂先天性心脏畸形胎儿，检出率为0.29%。超声筛查对心内膜垫缺损、大动脉转位、单心房/单心室、左心/右心发育不良、永存动脉干、主动脉弓中断、左室横纹肌瘤、法洛四联征、合并心外畸形及室间隔缺损的检出率与随访结果比较，差异无统计学意义（P >0.05）；共漏诊5例（0.05%），其中法洛四联征1例、肺动脉狭窄2例、室间隔缺损2例。结论产前超声检查对妊娠中期胎儿复杂先天性心脏畸形的诊断准确率较高，能有效降低复杂先天性心脏畸形胎儿出生率，是实现优生优育的重要手段。
목적：탐토산전초성사사대임신중기태인복잡선천성심장기형적진단개치。방법회고성분석2012년2월-2014년2월재아원진행산전초성사사적9300례임신중기잉부적초성검사자료，비교초성검사결과화산후수방결과。결과9300례잉부공검출27례복잡선천성심장기형태인，검출솔위0.29%。초성사사대심내막점결손、대동맥전위、단심방/단심실、좌심/우심발육불량、영존동맥간、주동맥궁중단、좌실횡문기류、법락사련정、합병심외기형급실간격결손적검출솔여수방결과비교，차이무통계학의의（P >0.05）；공루진5례（0.05%），기중법락사련정1례、폐동맥협착2례、실간격결손2례。결론산전초성검사대임신중기태인복잡선천성심장기형적진단준학솔교고，능유효강저복잡선천성심장기형태인출생솔，시실현우생우육적중요수단。
Objective To explore the diagnostic value of prenatal ultrasound screening on fetuses with complex con-genital heart malformation in second trimester of pregnancy. Methods From February 2012 to February 2014,the examination data of prenatal ultrasound screening of 9 300 pregnant women in second trimester of pregnancy in our hospital were retrospectively analyzed,the ultrasound findings and follow - up results were compared. Results The positive rate of complex congenital heart malformation was 0. 29% (27 / 9 300). There was no significant differences of detection rate of endocardial cushion defect, transposition of the great arteries,single atrium or ventricle,left or right heart dysplasia,persistent truncus arteriosus,inter-rupted aortic arch,left ventricular cardiac rhabdomyoma,Fallot's tetrad,outside heart malformations and ventricular septal de-fect between ultrasound findings and the fellow - up results(P > 0. 05). A total of 5 cases(0. 05% )got missed diagnosis,in-cluding one case of Fallot's tetrad,2 cases of pulmonary artery stenosis,2 cases of ventricular septal defect. Conclusion Pre-natal ultrasound screening has a higher accurate diagnosis rate on fetuses with complex congenital heart malformation in second tri-mester of pregnancy,is helpful in reducing the birth rate of fetuses with complex congenital heart malformation and to prenatal and postnatal care.