CAJ | 학술논문

目的：探讨原发性脑干出血预后影响因素。方法选择我院2009年10月-2013年10月收治的原发性脑干出血患者80例，根据预后情况分为病死组48例和存活组32例，观察两组患者出血量、年龄、意识情况、呼吸情况、体温及收缩压。结果本组患者病死率为60.0%（48/80），存活患者神经功能缺损发生率为62.5%（20/32）。病死组患者出血量、年龄、Borg 评分、体温、收缩压高于存活组，格拉斯哥昏迷量表（ GCS）评分低于存活组（ P <0.05）。线性回归分析结果显示，出血量、GCS 评分、Borg 评分、体温、收缩压与原发性脑干出血预后差关系的回归方程分别为：y出血量=5.83-0.18x（ R2=0.998）、yGCS评分=25.26-1.25x（ R2=0.946）、yBorg评分=2.35+0.31x（ R2=0.984）、y体温=2.38-0.09x（R2=0.996）、y收缩压=23.44x（R2=0.992），而年龄与原发性脑干出血预后差无线性回归关系。结论大量出血、意识不清、呼吸抑制或呼吸衰竭、发热、高血压是导致原发性脑干出血患者预后差的重要原因。
목적：탐토원발성뇌간출혈예후영향인소。방법선택아원2009년10월-2013년10월수치적원발성뇌간출혈환자80례，근거예후정황분위병사조48례화존활조32례，관찰량조환자출혈량、년령、의식정황、호흡정황、체온급수축압。결과본조환자병사솔위60.0%（48/80），존활환자신경공능결손발생솔위62.5%（20/32）。병사조환자출혈량、년령、Borg 평분、체온、수축압고우존활조，격랍사가혼미량표（ GCS）평분저우존활조（ P <0.05）。선성회귀분석결과현시，출혈량、GCS 평분、Borg 평분、체온、수축압여원발성뇌간출혈예후차관계적회귀방정분별위：y출혈량=5.83-0.18x（ R2=0.998）、yGCS평분=25.26-1.25x（ R2=0.946）、yBorg평분=2.35+0.31x（ R2=0.984）、y체온=2.38-0.09x（R2=0.996）、y수축압=23.44x（R2=0.992），이년령여원발성뇌간출혈예후차무선성회귀관계。결론대량출혈、의식불청、호흡억제혹호흡쇠갈、발열、고혈압시도치원발성뇌간출혈환자예후차적중요원인。
Objective To investigate influencing factors of prognosis in patients with primary brain stem hemorrhage. Methods A total of 80 patients with primary brain stem hemorrhage admitted to our hospital from October 2009 to October 2013 were selected,and they were divided into death group(n = 48)and survival group(n = 32)according to prognosis. Amount of bleeding,age,consciousness,respiratory,temperature and systolic pressure of the two groups were observed. Results The fatality rate was 60. 0% (48 / 80),the incidence of neurological function deficit in survival group was 62. 5% (20 / 32). A-mount of bleeding,age,Borg score,temperature and systolic pressure of death group were higher than those of survival group, while GCS score was lower(P < 0. 05). Linear - regression analysis results showed that,amount of bleeding,GCS score,Borg score,temperature,systolic pressure was correlated with poor prognosis of primary brain stem hemorrhage,respectively,and the regression equation was y = 5. 83 - 0. 18x( R2 = 0. 998),y = 25. 26 - 1. 25x( R2 = 0. 946),y = 2. 35 + 0. 31x( R2 =0. 984),y = 2. 38 - 0. 09x(R2 = 0. 996),y = 23. 44x(R2 = 0. 992),respectively. There was no linear - regression correla-tion between age and poor prognosis of primary brain stem hemorrhage. Conclusion Larger amount of bleeding,unconscious-ness,respiratory depression or failure,fever,hypertension were influencing factors of poor prognosis in patients with primary brain stem hemorrhage.