CAJ | 학술논문

目的：提高痰培养流感嗜血杆菌的检出率，了解其耐药性，为经验用药提供依据。方法对本院近两年来痰标本分离的流感嗜血杆菌，总结分离培养经验及药敏结果，采用WHONET5.6软件处理数据。结果痰培养共分离流感嗜血杆菌61株，对复方新诺明、四环素、氨苄西林的耐药率较高，分别是50.8％、37.7％和27.9％，对左氧氟沙星等耐药率小于10％。结论微生物室在痰培养中应从控制合格痰标本等环节提高流感嗜血杆菌的检出率。左氧氟沙星等大多数药物耐药率较低，可作为治疗流感嗜血杆菌感染的经验药物，复方新诺明、四环素不适合临床经验用药。
목적：제고담배양류감기혈간균적검출솔，료해기내약성，위경험용약제공의거。방법대본원근량년래담표본분리적류감기혈간균，총결분리배양경험급약민결과，채용WHONET5.6연건처리수거。결과담배양공분리류감기혈간균61주，대복방신낙명、사배소、안변서림적내약솔교고，분별시50.8％、37.7％화27.9％，대좌양불사성등내약솔소우10％。결론미생물실재담배양중응종공제합격담표본등배절제고류감기혈간균적검출솔。좌양불사성등대다수약물내약솔교저，가작위치료류감기혈간균감염적경험약물，복방신낙명、사배소불괄합림상경험용약。
Objective To increase the detection rate of Haemophitus Inlfuenzae in sputum culture and investigate the antibiotic resistance of clinical isolates of haemophilus inlfuenzae for providing basis of the empirical antibiotic use.Method The experience of isolated culture and the antimicrobial susceptibility result was summarized to Haemophitus Inlfuenzae in sputum culture in the last two years. WHONET 5.6 software was used to process data. Results 61 strains haemophilus influenzae were separated from sputum culture, Resistant rate of haemophilus inlfuenzae to TMP/SMZ,tetracycline,ampicillin were higher,they were 50.8%, 39.7% and 27.9%, respectively, while resistant rate of levolfoxacin etc was less than 10%.Conclusion Moicrobiology lab should improve the detection rate from controlling the qualified sputum specimen etc in sputum culture.The resistant rate to the majority of antibiotic such as levolfoxacin is low,they are suitable to treat infections caused by haemophilus inlfuenzae for experiential therapy, TMP/SMZ, tetracycline are unsuitable.