海峡药学
海峽藥學
해협약학
STRAIT PHARMACEUTICAL JOURNAL
2014年
10期
85-86
,共2页
肾结石%肾绞痛%地佐辛%间苯三酚
腎結石%腎絞痛%地佐辛%間苯三酚
신결석%신교통%지좌신%간분삼분
Renal calculus%Renal colic%Dezocine%Pholorglucinol
目的：观察地佐辛与间苯三酚合用治疗结石性肾绞痛临床疗效。方法肾绞痛患者178例，分为两组。实验组94例，组肌注地佐辛5mg，静脉滴注间苯三酚120mg；对照组84例，肌注杜冷丁50mg，静滴山莨菪碱10mg；观察解痉、镇痛效果及其不良反应。结果实验组和对照组总有效率分别为91.5％、89.3％，组间无显著性差异（ P＞0.05）；实验组、对照组6 h内疼痛再发率分别为13.8％、33.3％，组间有显著性差异（P＜0.05）；实验组和对照组的不良反应发生率分别为22.3％、47.6％，组间有显著性差异（P＜0.05）。结论地佐辛与间苯三酚合用治疗肾绞痛疗效好，不良反应少。
目的：觀察地佐辛與間苯三酚閤用治療結石性腎絞痛臨床療效。方法腎絞痛患者178例，分為兩組。實驗組94例，組肌註地佐辛5mg，靜脈滴註間苯三酚120mg；對照組84例，肌註杜冷丁50mg，靜滴山莨菪堿10mg；觀察解痙、鎮痛效果及其不良反應。結果實驗組和對照組總有效率分彆為91.5％、89.3％，組間無顯著性差異（ P＞0.05）；實驗組、對照組6 h內疼痛再髮率分彆為13.8％、33.3％，組間有顯著性差異（P＜0.05）；實驗組和對照組的不良反應髮生率分彆為22.3％、47.6％，組間有顯著性差異（P＜0.05）。結論地佐辛與間苯三酚閤用治療腎絞痛療效好，不良反應少。
목적：관찰지좌신여간분삼분합용치료결석성신교통림상료효。방법신교통환자178례，분위량조。실험조94례，조기주지좌신5mg，정맥적주간분삼분120mg；대조조84례，기주두랭정50mg，정적산랑탕감10mg；관찰해경、진통효과급기불량반응。결과실험조화대조조총유효솔분별위91.5％、89.3％，조간무현저성차이（ P＞0.05）；실험조、대조조6 h내동통재발솔분별위13.8％、33.3％，조간유현저성차이（P＜0.05）；실험조화대조조적불량반응발생솔분별위22.3％、47.6％，조간유현저성차이（P＜0.05）。결론지좌신여간분삼분합용치료신교통료효호，불량반응소。
OBJECTIVE To investigate the clinical effects of dezocine combined with pholroglucinol on renal colic caused by calculus.METHODS 178 cases of renal colic patients were divided into experiment group ( n=94 ) and control group ( n=84 ).Experiment group:intramuscular dezocine 5 mg combined with intravenous pholro-glucinol 120mg.Control group: intramuscular demerol 50mg combined with intravenous anisodamine 10 mg.Spasmolysis effects ,analgesia effects and side effects in each group were observed.RESULTS There were no significant differences in total effective rate which were 91.5%,89.3%in experiment group and control respectively ( P>0.05 ) ,and statistically significant differences in the incidences of side effects which were 22.3%and 47.6%in experiment group and control respectively ( P<0.05 ).CONCLUSION There are remarkable clinical effects and low incidence of side effect of dezocine combined with benzene three phenol on renal colic caused by calculus .
