CAJ | 학술논문

目的：分析中老年女性乳腺纤维腺瘤的 MRI 的特点，以期提高中老年女性乳腺纤维腺瘤的诊断准确率。方法：搜集2013年1月-2014年7月手术病理证实为纤维腺瘤且术前行 MRI 检查的患者共162例（217个病灶），本研究将患者分为年轻组（＜40岁）156例和中老年组（≥40岁）61例。分析病灶的形态学特点、表观扩散系数（ADC）及动态增强特点。结果：本组乳腺纤维腺瘤形态以分叶状（42．4％，92/217）及类圆形（40．1％，87/217）为主，少数为圆形（13．8％，30/217）及不规则形（1．4％，3/217）。边缘清楚者占92．2％（200/217），不清楚者占7．8％（17/217）。年轻组及中老年组在病灶形态及边缘上的差别均无统计学意义（P ＞0．05）。内部强化以均匀强化（53．5％，116/217）及不均匀强化（44．7％，97/217）为主，少数表现为环形强化（0．5％，1/217）及不强化（1．4％，3/217），两组内部强化构成比差异有统计学意义（P ＝0．01）。年轻组 ADC 值中位数为1．60×10-3 mm2/s，略低于中老年组 ADC 值中位数（1．67×10-3 mm2/s），两组差异均无统计学意义（Z ＝-1．55，P ＝0．121）。结论：乳腺纤维腺瘤在 MRI 多表现边缘清楚的类圆形或分叶状肿块，增强以均匀及不均匀强化为主。中老年组纤维腺瘤在形态学及 ADC 值上与年轻组无统计学差异。
목적：분석중노년녀성유선섬유선류적 MRI 적특점，이기제고중노년녀성유선섬유선류적진단준학솔。방법：수집2013년1월-2014년7월수술병리증실위섬유선류차술전행 MRI 검사적환자공162례（217개병조），본연구장환자분위년경조（＜40세）156례화중노년조（≥40세）61례。분석병조적형태학특점、표관확산계수（ADC）급동태증강특점。결과：본조유선섬유선류형태이분협상（42．4％，92/217）급류원형（40．1％，87/217）위주，소수위원형（13．8％，30/217）급불규칙형（1．4％，3/217）。변연청초자점92．2％（200/217），불청초자점7．8％（17/217）。년경조급중노년조재병조형태급변연상적차별균무통계학의의（P ＞0．05）。내부강화이균균강화（53．5％，116/217）급불균균강화（44．7％，97/217）위주，소수표현위배형강화（0．5％，1/217）급불강화（1．4％，3/217），량조내부강화구성비차이유통계학의의（P ＝0．01）。년경조 ADC 치중위수위1．60×10-3 mm2/s，략저우중노년조 ADC 치중위수（1．67×10-3 mm2/s），량조차이균무통계학의의（Z ＝-1．55，P ＝0．121）。결론：유선섬유선류재 MRI 다표현변연청초적류원형혹분협상종괴，증강이균균급불균균강화위주。중노년조섬유선류재형태학급 ADC 치상여년경조무통계학차이。
Objective:To evaluate magnetic resonance imaging (MRI)findings of breast fibroadenoma in elder woman in order to improve the diagnostic accuracy.Methods:This retrospective study evaluated 162 patients (217 lesions)with pathologically-confirmed breast fibroadenoma in our hospital between January 2013 and July 2014.All the patients under-went MRI examination before operation.Morphological characteristics,apparent diffusion coefficient (ADC)values,and he-modynamic characteristics were reviewed.All the patients were divided into two groups according to ages,the younger group (age <40 years,156 cases)and the elder group (age≥40 years,61 cases).Results:The shapes of breast fibroadeno-ma were more commonly lobulated (42.4%,92/217)and oval (40.1%,87/217),less frequently round (13.8%,30/217), and irregular (1.4%,3/217).The margins were circumscribed in 92.2% (200/217)of cases and not circumscribed in the remaining 7.8% (17/217).No significant differences in shape and margin were observed between the younger group and elder group.The internal enhancement of breast fibroadenoma were more commonly homogeneous (53.5%,116/217)and heterogeneous (44.7%,97/217),less frequently rim-enhanced (0.5%,1/217)and non-enhanced (1.4%,3/217),with a statistically significant difference on composition of the internal enhancement between the two groups (P =0.010).The me-dian ADC value of the lesion in the younger group was 1.60 × 10 -3 mm2/s,slightly lower than that of the elder group (1.67×10 -3 mm2/s),however,no significant difference was found (Z =-1.55,P =0.121).Conclusions:Breast fibroade-noma commonly shows a lobulated or oval mass with circumscribed margin,and homogeneous or heterogeneous enhance-ment.There was no significant difference in the morphology and ADC values between the younger group and the elder group.