CAJ | 학술논문

目的：探讨婴幼儿期食入性与吸入性过敏原的特点及其相互关系。方法：使用UniCAP系统测定370例过敏患儿血清特异性牛奶IgE、鸡蛋IgE、尘螨IgE水平,分析3种过敏原在各年龄段的过敏率,以及吸入性过敏原与食入性过敏原有否存在交叉过敏现象。结果：牛奶与鸡蛋的过敏率随着年龄增长呈下降趋势,3岁后过敏率明显降低；而尘螨的过敏率则随着年龄增高呈上升趋势,2岁后过敏率明显增高。>2~3岁牛奶与尘螨存在交叉过敏,其余阶段无交叉过敏。结论：婴幼儿早期过敏以食物性过敏为主,随着年龄增长可逐渐产生耐受,向吸入性过敏原方向发展,故在食物过敏症状减轻时,仍需警惕吸入性过敏原诱发的过敏现象。
목적：탐토영유인기식입성여흡입성과민원적특점급기상호관계。방법：사용UniCAP계통측정370례과민환인혈청특이성우내IgE、계단IgE、진만IgE수평,분석3충과민원재각년령단적과민솔,이급흡입성과민원여식입성과민원유부존재교차과민현상。결과：우내여계단적과민솔수착년령증장정하강추세,3세후과민솔명현강저；이진만적과민솔칙수착년령증고정상승추세,2세후과민솔명현증고。>2~3세우내여진만존재교차과민,기여계단무교차과민。결론：영유인조기과민이식물성과민위주,수착년령증장가축점산생내수,향흡입성과민원방향발전,고재식물과민증상감경시,잉수경척흡입성과민원유발적과민현상。
Objective:To determine the characteristics of ingested allergens and inhaled allergens in infancy and the relationship between them. Methods:370 infants with allergic diseases were included in this study. Serum-specific IgE to milk, egg and pyroglyphidae were measured in all the patients with UniCAP System;the allergic rate of the three kinds of allergens in different ages, the cross allergy phenomenon between ingested allergens and inhaled allergens were all analyzed. Results:The prevalence of milk allergy and egg allergy went down with the age increasing,and the prevalence decreased obviously after the age of 3;The prevalence of pyroglyphidae allergy went down with the age increasing,and the prevalence increased obviously after the age of 2. There was no cross allergic phenomenon between the milk and pyroglyphidae except the >2 -3 age group. Conclusions:Allergic phenomena in infancy and early childhood are mainly caused by ingested allergens,and will gradually develop tolerance with the age increasing and turn to inhalant allergens. So when ingested allergy symptoms are relieved, attention still should be paid to inhaled allergen-induced allergic phenomena.