中国药业
中國藥業
중국약업
CHINA PHARMACEUTICALS
2014年
20期
19-20,21
,共3页
氯吡格雷%瑞舒伐他汀钙%短暂性脑缺血%优质护理
氯吡格雷%瑞舒伐他汀鈣%短暫性腦缺血%優質護理
록필격뢰%서서벌타정개%단잠성뇌결혈%우질호리
clopidogrel%rosuvastatin calcium%transient cerebral ischemia%high quality care
目的：探讨氯吡格雷联合瑞舒伐他汀钙对短暂性脑缺血（TIA）的临床疗效，以及其对患者生存质量的改善效果。方法按入院顺序将95例TIA患者随机分成两组。对照组48例患者常规给予阿司匹林肠溶片100 mg/d；治疗组47例患者在此基础上给予硫酸氢氯吡格雷片75 mg/d，瑞舒伐他汀钙片10 mg/d（睡前服用）。治疗第7个月时实施优质护理行动，观察其对TIA患者的影响。结果通过14个月的治疗，对照组总有效率为62.50%，发作频率（3.2±1.5）次/月；治疗组总有效率为80.85%，发作频率（1.8±0.2）次/月；治疗后，治疗组血小板计数( PLT )明显降低，凝血活酶时间( APTT )、凝血酶时间( PT )较治疗前延长（ P<0.05），对照组PLT，APTT，PT与治疗前比较差异无统计学意义；采用有针对性的优质护理服务后，患者对护理的满意度大大提高，医疗纠纷发生率降低。结论氯吡格雷联合瑞舒伐他汀钙大大提高了短暂性脑缺血的疗效，优质护理服务有利于降低医疗纠纷。
目的：探討氯吡格雷聯閤瑞舒伐他汀鈣對短暫性腦缺血（TIA）的臨床療效，以及其對患者生存質量的改善效果。方法按入院順序將95例TIA患者隨機分成兩組。對照組48例患者常規給予阿司匹林腸溶片100 mg/d；治療組47例患者在此基礎上給予硫痠氫氯吡格雷片75 mg/d，瑞舒伐他汀鈣片10 mg/d（睡前服用）。治療第7箇月時實施優質護理行動，觀察其對TIA患者的影響。結果通過14箇月的治療，對照組總有效率為62.50%，髮作頻率（3.2±1.5）次/月；治療組總有效率為80.85%，髮作頻率（1.8±0.2）次/月；治療後，治療組血小闆計數( PLT )明顯降低，凝血活酶時間( APTT )、凝血酶時間( PT )較治療前延長（ P<0.05），對照組PLT，APTT，PT與治療前比較差異無統計學意義；採用有針對性的優質護理服務後，患者對護理的滿意度大大提高，醫療糾紛髮生率降低。結論氯吡格雷聯閤瑞舒伐他汀鈣大大提高瞭短暫性腦缺血的療效，優質護理服務有利于降低醫療糾紛。
목적：탐토록필격뢰연합서서벌타정개대단잠성뇌결혈（TIA）적림상료효，이급기대환자생존질량적개선효과。방법안입원순서장95례TIA환자수궤분성량조。대조조48례환자상규급여아사필림장용편100 mg/d；치료조47례환자재차기출상급여류산경록필격뢰편75 mg/d，서서벌타정개편10 mg/d（수전복용）。치료제7개월시실시우질호리행동，관찰기대TIA환자적영향。결과통과14개월적치료，대조조총유효솔위62.50%，발작빈솔（3.2±1.5）차/월；치료조총유효솔위80.85%，발작빈솔（1.8±0.2）차/월；치료후，치료조혈소판계수( PLT )명현강저，응혈활매시간( APTT )、응혈매시간( PT )교치료전연장（ P<0.05），대조조PLT，APTT，PT여치료전비교차이무통계학의의；채용유침대성적우질호리복무후，환자대호리적만의도대대제고，의료규분발생솔강저。결론록필격뢰연합서서벌타정개대대제고료단잠성뇌결혈적료효，우질호리복무유리우강저의료규분。
Objective To investigate the clinical effect of clopidogrel combined with rosuvastatin calcium in treating transient cerebral is-chemia(TIA),and to explore the improvement effect of quality of life in the patients by conducting simultaneous high quality nursing service. Methods 95 patients with TIA were randomly divided into two groups according to the sequence number of admission. The control group(48 cases)was treated with the conventional medicine Aspirin Enteric-Coated Tablets 100 mg/d;on this basis the treat-ment group(47 cases)was given Clopidogrel Hydrogen Sulfate Tablet 75 mg/d,Rosuvastatin Calcium Tablet 10 mg/d(before sleep). In 7 months during the treatment,the high quality nursing service was implemented in our hospital. Thus the effect of the high quality nursing service on the TIA patients was observed. Results The total effective rate after 14-month treatment in the control group was 62.50%,the seizure frequency was(3.2±1.5)times/month,which in the treatment group were 80.85% and(1.8±0.2)times/month respectively;PLT after treatment in the treatment group was significantly reduced( P < 0. 05),APTT and PT were prolonged compared with before treatment;while PLT,APTT and PT in the control group had no statistical differences between before and after treatment;af-ter the adopting targeted high quality care service,the patient satisfaction on the nursing care was greatly increased and the occurrence rate of medical disputes was significantly decreased. Conclusion Clopidogrel combined with rosuvastatin calcium enormously increases the effect in treating treatment TIA,the high quality nursing service conduces to reduces the medical disputes.
