CAJ | 학술논문

目的：探讨急性结膜炎患者治疗前后血清hs-CRP、Il-6和β-防御素-3水平的变化及临床意义。方法应用免疫比浊法，放射免疫分析法和酶联法对40例急性结膜炎患者进行了血清hs-CRP、Il-6和β-防御素-3的水平检测，并与35名正常健康人作比较。结果急性结膜炎患者在治疗前血清hs-CRP、Il-6水平非常显著地高于正常人组（P＜0．01），而β-防御素-3水平显著地低于正常人组（P＜0．01），经中西医结合治疗2周后则与正常人比较无显著性差异（ P＞0．05）。结论检测急性结膜炎患血清hs-CRP、Il-6和β-防御素-3水平的变化对临床观察预后均有重要的临床价值。
목적：탐토급성결막염환자치료전후혈청hs-CRP、Il-6화β-방어소-3수평적변화급림상의의。방법응용면역비탁법，방사면역분석법화매련법대40례급성결막염환자진행료혈청hs-CRP、Il-6화β-방어소-3적수평검측，병여35명정상건강인작비교。결과급성결막염환자재치료전혈청hs-CRP、Il-6수평비상현저지고우정상인조（P＜0．01），이β-방어소-3수평현저지저우정상인조（P＜0．01），경중서의결합치료2주후칙여정상인비교무현저성차이（ P＞0．05）。결론검측급성결막염환혈청hs-CRP、Il-6화β-방어소-3수평적변화대림상관찰예후균유중요적림상개치。
Objective To explore the clinical significance of serum hs-CRP, Il-6 and beta-defensin-3 levels in patients with acute conjunctivitis after treatment .Methods Serum hs-CRP ( with immumo-turbidity ) Serum Il-6(with RIA), Serum beta-defensin-3(with ElisA) levels were measured in 40 patients with acute conjunctivitis before and after treatment as well as in 35 controls.Results Before treatment , Serum Il-6, hs-CRP levels in the patients were significantly higher than those in controls (P<0.01),but Serum beta-defensin-3 levels were significantly lower(P<0.01).After treatment for 2 weeks, there were no significance between the levels in patients and controls (P>0.05).Conclusions Detection of serum hs-CRP, Il-6 and bata-defensin-3 levels after treatment might be important for outcome prediction in patients with acute conjumctivitis .