CAJ | 학술논문

目的：探讨糖尿病患者血清甲状腺激素相关指标的变化及发生甲状腺功能异常的概率。方法选择86例2型糖尿病患者采用电化学发光法测定其血清 FT3、FT4和 TSH 水平，并选择61例年龄、性别相匹配的健康体检者作为对照组。结果2型糖尿病患者血清 FT3、FT4和 TSH 水平的检测结果平均值分别为5．09 pmol/L、17．32 pmol/L 和2．81 mIU/L。对照组的血清FT3、FT4和 TSH 水平的平均值分别为4．99 pmol/L、17．24 pmol/L 和2．71 mIU/L，糖尿病组同对照组比较，差异无统计学意义（P ＞0．05）。86例糖尿病组中共有29例患者 TSH 异常，异常率为33．7％，对照组为14．8％，经χ2检验，差异有统计学意义（P ＜0．05）。糖尿病患者中，女性的 TSH 异常率为42．1％，高于糖尿病患者中男性的 TSH 异常率（17．2％）。结论对糖尿病患者进行血清甲状腺激素的检测十分有必要，尤其是女性患者，以利于早期筛查和防治。
목적：탐토당뇨병환자혈청갑상선격소상관지표적변화급발생갑상선공능이상적개솔。방법선택86례2형당뇨병환자채용전화학발광법측정기혈청 FT3、FT4화 TSH 수평，병선택61례년령、성별상필배적건강체검자작위대조조。결과2형당뇨병환자혈청 FT3、FT4화 TSH 수평적검측결과평균치분별위5．09 pmol/L、17．32 pmol/L 화2．81 mIU/L。대조조적혈청FT3、FT4화 TSH 수평적평균치분별위4．99 pmol/L、17．24 pmol/L 화2．71 mIU/L，당뇨병조동대조조비교，차이무통계학의의（P ＞0．05）。86례당뇨병조중공유29례환자 TSH 이상，이상솔위33．7％，대조조위14．8％，경χ2검험，차이유통계학의의（P ＜0．05）。당뇨병환자중，녀성적 TSH 이상솔위42．1％，고우당뇨병환자중남성적 TSH 이상솔（17．2％）。결론대당뇨병환자진행혈청갑상선격소적검측십분유필요，우기시녀성환자，이리우조기사사화방치。
Objective To explore the change of serum thyroid hormone related indicators and the probability of occurrence of thyroid dysfunction abnormality in the patient with type 2 diabetes mellitus(T2DM).Methods 86 patients with T2DM and 61 age-matched and gender-matched individuals with healthy physical examination as controls were selected and detected serum FT3,FT4 and TSH by the electrochemiluminescence method Results The serum FT3,FT4 and TSH in the T2DM group were 5.09 pmol/L, 17.32 pmol/L and 2.81 mIU/L respectively;which in the normal control group were 4.99 pmol/L,17.24 pmol/L and 2.71 mIU/L respectively,the differences between the two groups had no statistical significance(P >0.05).Among 86 cases of T2DM,29 cases had the serum abnormal TSH with the abnormal rate of 33.7%,which in the control group was 14.8% with statistical difference between the two groups(P <0.05).Among T2DM patients,the TSH abnormal rate of in females was 42.1%,which was higher than 17.2% in males.Conclusion The serum thyroid hormone detection is necessary for the T2DM patients,especially female pa-tients,which is conducive to early screening,prevention and treatment.