CAJ | 학술논문

目的：观察伊托必利联合聚乙二醇在慢性便秘患者结肠镜检查前肠道准备的效果。方法：120例拟行结肠镜检查的慢性便秘患者随机分为治疗组和对照组。治疗组：在服用伊托必利150 mg 半小时后，服用聚乙二醇；对照组：直接服用聚乙二醇。比较两组患者的肠道清洁效果、首次大便时间、大便清澈时间、大便次数、记录患者的不良反应。结果：治疗组患者肠道清洁度总体评分优于对照组(P<0.05)；治疗组患者首次大便时间、大便清澈时间短于对照组(P<0.05)；而两组间排便次数和肠道气泡评分差异无统计学意义(P>0.05)。结论：伊托必利联合聚乙二醇能安全、有效改善慢性便秘患者肠道准备的清洁度，缩短首次大便时间和大便清澈时间。
목적：관찰이탁필리연합취을이순재만성편비환자결장경검사전장도준비적효과。방법：120례의행결장경검사적만성편비환자수궤분위치료조화대조조。치료조：재복용이탁필리150 mg 반소시후，복용취을이순；대조조：직접복용취을이순。비교량조환자적장도청길효과、수차대편시간、대편청철시간、대편차수、기록환자적불량반응。결과：치료조환자장도청길도총체평분우우대조조(P<0.05)；치료조환자수차대편시간、대편청철시간단우대조조(P<0.05)；이량조간배편차수화장도기포평분차이무통계학의의(P>0.05)。결론：이탁필리연합취을이순능안전、유효개선만성편비환자장도준비적청길도，축단수차대편시간화대편청철시간。
Objective:To investigate the effect of colonoscopy preparation before endoscopy examination in constipated patients combined use of Itopride and polyethylene glycol(PEG). Methods:A total of 120 chronic constipation patients who underwent colonoscopy examination were recruited to this randomized controlled study. Patients in control group received PEG only,whereas patients in experimental group received 150mg Itopride 30min before PEG. The quality of colon cleansing、time of first defecation、time of completion of bowel cleansing、defecation frequency were comparison and side effects were recorded in both group. Results: The bowel cleaning quality in experimental group was better than that of control group(P< 0.05);The time of first defecation and completion of bowel cleaning of experimental group were shouter than those of control group (P<0.05);There was no significant difference in terms of the defecation frequency and intestinal bubble scores in both groups( P>0. 05).Conclusion: Combination of Itopride and PEG for colonoscopy preparation of patients with constipated can safely and effectively improve the bowel cleaning quality,short time of first defecation and completion of bowel cleaning.