CAJ | 학술논문

目的：探讨乳腺专用伽马成像（ BSGI）在乳腺癌诊断中的意义。方法对2012年3月至2013年12月本院收治的136例体格检查发现或偶然发现乳腺肿块、拟行手术的女性患者进行前瞻性研究，检测BSGI高低浓聚值比，并将BSGI结果与病理结果进行对比。采用Mann-Whitney U非参数检验分析良、恶性肿瘤之间BSGI高低浓聚值比的差异。结果 BSGI诊断乳腺癌的灵敏度、特异度、准确性、阳性预测值和阴性预测值分别为95.1％（97/102）、73.5％（25/34）、89.7％（122/136）、91.5％（97/106）、83.3％（25/30）。乳腺癌的 BSGI 高低浓聚值比明显高于良性肿瘤（2.98±1.29比0.95±1.11，Z＝-7.125，P＝0.000）。结论 BSGI对于乳腺癌的诊断具有很好的临床应用价值。
목적：탐토유선전용가마성상（ BSGI）재유선암진단중적의의。방법대2012년3월지2013년12월본원수치적136례체격검사발현혹우연발현유선종괴、의행수술적녀성환자진행전첨성연구，검측BSGI고저농취치비，병장BSGI결과여병리결과진행대비。채용Mann-Whitney U비삼수검험분석량、악성종류지간BSGI고저농취치비적차이。결과 BSGI진단유선암적령민도、특이도、준학성、양성예측치화음성예측치분별위95.1％（97/102）、73.5％（25/34）、89.7％（122/136）、91.5％（97/106）、83.3％（25/30）。유선암적 BSGI 고저농취치비명현고우량성종류（2.98±1.29비0.95±1.11，Z＝-7.125，P＝0.000）。결론 BSGI대우유선암적진단구유흔호적림상응용개치。
Objective To evaluate the clinical significance of breast-specific gamma imaging ( BSGI) in diagnosis of breast cancer .Methods We performed a perspective study of 136 patients with indeterminate breast lesions who underwent dual-phase BSGI in our hospital from March 2012 to December 2013 .All included lesions were confirmed by pathology .BSGI was evaluated based on the visual interpretation and dual -phase semi-quantitative indices of lesion to non-lesion ( L/N) ratio, which were compared with pathological results . Difference of L/N ratio of BSGI between benign and malignant breast lesions was analyzed by Mann -Whitney U nonparametric test.Results The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of BSGI in the diagnosis of breast cancer were 95.1%( 97/102 ) , 73.5%( 25/34 ) , 89.7%(122/136), 91.5%(97/106) and 83.3%(25/30), respectively.L/N ratio of BSGI in breast cancer was significantly higher than that of benign tumor ( 2.98 ±1.29 vs 0.95 ±1.11 , Z=-7.125 , P=0.000 ) . Conclusion BSGI has a significant clinical value in the diagnosis of breast cancer .