CAJ | 학술논문

目的总结儿童恶性肿瘤破裂的临床表现，探讨诊断方法及相应治疗措施。方法回顾我院自2008年以来收治的14例恶性肿瘤破裂患儿的病例资料，归纳其发病特点，对治疗方案及效果进行分析，并进行长期随访。结果14例患儿中，肝母细胞瘤5例，肾母细胞瘤5例，其他类型恶性肿瘤4例。10例以腹痛伴低血容量性休克表现入院。全部病例均确诊肿瘤破裂并给予抗休克等对症治疗，7例接受急诊手术，其中5例切除肿瘤，2例手术止血。11例患儿进行抢救性化疗。10例患儿经过治疗后，病情得到不同程度缓解出院。对9例出院患儿进行长期随访，6例存活，3例复发死亡。结论儿童恶性肿瘤破裂以低血容量休克为主要临床表现，入院后需要进行综合治疗，主要包括对症止血、抗休克，抢救性化疗和急诊手术。经过治疗，大部分患儿可以赢得继续治疗的机会，病情最终得到缓解。
목적총결인동악성종류파렬적림상표현，탐토진단방법급상응치료조시。방법회고아원자2008년이래수치적14례악성종류파렬환인적병례자료，귀납기발병특점，대치료방안급효과진행분석，병진행장기수방。결과14례환인중，간모세포류5례，신모세포류5례，기타류형악성종류4례。10례이복통반저혈용량성휴극표현입원。전부병례균학진종류파렬병급여항휴극등대증치료，7례접수급진수술，기중5례절제종류，2례수술지혈。11례환인진행창구성화료。10례환인경과치료후，병정득도불동정도완해출원。대9례출원환인진행장기수방，6례존활，3례복발사망。결론인동악성종류파렬이저혈용량휴극위주요림상표현，입원후수요진행종합치료，주요포괄대증지혈、항휴극，창구성화료화급진수술。경과치료，대부분환인가이영득계속치료적궤회，병정최종득도완해。
Objective To summary the clinical manifestations of ruptured malignant tumors and investigate its diagnosis and treatment.Methods A retrospective study of 1 4 cases with ruptured malignant tumors from 2008 to 201 4 were retrospectively analyzed.Results In our study,there were 5 cases of hepatoblastoma,5 cases of nephroblastoma and 4 cases of other pathological types.All were admitted to our hospital for the symptoms of abdominal pain accompanied with hypovolemic shock.All the cases were confirmed to have rupture of tumors and received symptomatic treatment including anti-shock. 7 patients had received emergency surgery,tumors had been removed in 5 patients and 2 cases had developed surgical hemostasis.1 1 cases had received salvage chemotherapy.After treatment,1 0 patients discharged hospital with varying improvement.We made long-term follow-up in 9 patients,6 were survival,3 died of recurrence.Conclusions Children with malignant tumors ruptured usually have hypovolemic shock which might be the main clinical performance.Comprehensive treatment becomes necessary after admission, including symptomatic anti-bleeding, anti-shock, salvage chemotherapy, surgery and other emergency measures. After treatment, most patients are capable of getting the opportunity to continue treatment,and ultimately make the disease remission.