CAJ | 학술논문

建立了固相萃取-液相色谱-串联质谱组合联用技术同时测定地表水、饮用水和污水处理厂出厂水中的5种雌激素（17β-雌二醇、雌三醇、雌酮、17α-炔雌醇、己烯雌酚）的方法。水样经过全自动固相萃取仪富集，以OASIS HLB柱为萃取柱，甲醇为洗脱剂，用液相色谱-串联四极杆质谱联用仪分析定量。分别在0?5～8、5～80μg/L范围内线性良好，相关系数为0?995～0?998。17β-雌二醇、雌三醇、17α-炔雌醇的检出限均为5μg/L，雌酮与己烯雌酚的检出限为0?5μg/L。5种雌激素的纯水加标回收率为63?6％～120?2％，地表水加标回收率为59?8％～91?5％，自来水加标回收率为55?3％～92?1％，精密度为3?7％～10?7％，该方法简单、可靠，可用于水中雌激素类污染物的同时测定。
건립료고상췌취-액상색보-천련질보조합련용기술동시측정지표수、음용수화오수처리엄출엄수중적5충자격소（17β-자이순、자삼순、자동、17α-결자순、기희자분）적방법。수양경과전자동고상췌취의부집，이OASIS HLB주위췌취주，갑순위세탈제，용액상색보-천련사겁간질보련용의분석정량。분별재0?5～8、5～80μg/L범위내선성량호，상관계수위0?995～0?998。17β-자이순、자삼순、17α-결자순적검출한균위5μg/L，자동여기희자분적검출한위0?5μg/L。5충자격소적순수가표회수솔위63?6％～120?2％，지표수가표회수솔위59?8％～91?5％，자래수가표회수솔위55?3％～92?1％，정밀도위3?7％～10?7％，해방법간단、가고，가용우수중자격소류오염물적동시측정。
A liquid chromatography-mass spectrometric ( LC-MS-MS ) method was established for the determination of five estrogens in surface water , drinking water and waste water. The sample was enriched with by solid-phase extraction column, extracted with methanol, evaporated by nitrogen, redissolved by acetonitrile/water(3∶2,V/V) and then analyzed by LC-MS-MS. Under the optimal conditions, good linearities were obtained in the range of 0?5-8 μg/L and 5-80 μg/L with correlation coefficients of 0?995-0?998. The limits of 17B-estradiol, estriol and 17α-ethiny lestradiol were all 5 μg/L and the limits of estrone and diethylstilbestrol were all 0?5μg /L. The recoveries of five estrogens in pure water,surface water and drinking water were 63?6%-120?2%, 59?8%-91?5% and 55?3%-92?1%. The relative standard deviations ranged from 3?7% to 10?7%. The method was simple and reliable and it could be used to determinate five estrogens in water at the same time.