CAJ | 학술논문

目的：分析我院2012~2013年抗肿瘤类中药注射剂的应用情况，为临床合理用药提供参考。方法采用回顾性调查的方法对我院2012~2013年抗肿瘤类中药注射剂的品种、抗肿瘤类中药注射剂用药总金额在中药注射剂用药总金额中的构成比、单品种抗肿瘤类中药注射剂用药金额在抗肿瘤类中药注射剂用药总金额中的构成比、用药频度（DDDs）、日用药金额（DDC）及药物不良反应发生率进行统计分析。结果2012～2013年，我院共有4种抗肿瘤类中药注射剂，其用药总金额与构成比变化均不明显；康艾注射液的用药金额、构成比、DDDs均连续两年位居第一，且呈较大幅度上升，2013年的构成比达到85.09％；艾迪注射液的的用药金额、构成比、DDDs下降幅度较大；4个品种的DDC均无显著变化；抗肿瘤类中药注射剂不良反应发生率较低。结论康艾注射液在抗肿瘤类中药注射剂中占主导地位，但用药结构不合理，需要进一步加强管理与监督。
목적：분석아원2012~2013년항종류류중약주사제적응용정황，위림상합리용약제공삼고。방법채용회고성조사적방법대아원2012~2013년항종류류중약주사제적품충、항종류류중약주사제용약총금액재중약주사제용약총금액중적구성비、단품충항종류류중약주사제용약금액재항종류류중약주사제용약총금액중적구성비、용약빈도（DDDs）、일용약금액（DDC）급약물불량반응발생솔진행통계분석。결과2012～2013년，아원공유4충항종류류중약주사제，기용약총금액여구성비변화균불명현；강애주사액적용약금액、구성비、DDDs균련속량년위거제일，차정교대폭도상승，2013년적구성비체도85.09％；애적주사액적적용약금액、구성비、DDDs하강폭도교대；4개품충적DDC균무현저변화；항종류류중약주사제불량반응발생솔교저。결론강애주사액재항종류류중약주사제중점주도지위，단용약결구불합리，수요진일보가강관리여감독。
Objective To analyze the application of anticancer traditional Chinese medicine(TCM) injection in our hos-pital from 2012 to 2013, and provide references for the rational clinical use of drug. Methods The drug varieties, constitu-ents ratio of total consumption of anticancer TCM injection in TCM injection, constituents ratio of total consumption of single varieties in anticancer TCM injection, DDDs, daily drug cost (DDC) and incidence of adverse drug reactions were analyzed with retrospective survey methodology. Results There were four varieties of anticancer TCM injection in our hospital. Their total consumption sum and constituents ratios all had little changes. The consumption sum, constituents ratio, DDDs of Kang’ai injection ranked first place for two consecutive years, and these index present a great increasing trend. In 2013, its constituents ratio reached up to 85.09%. The consumption sum, constituents ratio, DDDs of Aidi injection had been greatly decreased. No significant changes were found in the DDC of four drug varieties. All the investigated anticancer TCM injec-tion had a low incidence of adverse drug reactions. Conclusion Kang'ai injection was predominant in the anticancer TCM injection, but the structure of drug usage was not reasonable. The drug regulation and supervision were still needed to be further strengthened.