CAJ | 학술논문

目的：探讨血清25-(OH)D和总免疫球蛋白E(TIgE)与无明确基础疾病儿童反复性肺炎的关系。方法选取76例无明确基础疾病反复性肺炎及72例单次肺炎患儿作为观察组，儿童保健门诊体检的60名儿童作为对照组，测定三组血清25-(OH)D及总免疫球蛋白E(TIgE)含量。结果反复肺炎组血清25-(OH)D水平明显低于单次肺炎组和对照组，差异有统计学意义(P<0.05)，单次肺炎组血清25-(OH)D和对照组比较，差异无统计学意义(P>0.05)；反复肺炎组血清TIgE含量水平高于单次肺炎组和对照组(P<0.05)，单次肺炎组和对照组血清TIgE比较，差异无统计学意义(P>0.05)。结论维生素D缺乏可能是儿童患反复肺炎的诱因之一，在临床应加强儿童维生素D缺乏的预防、诊断和治疗。
목적：탐토혈청25-(OH)D화총면역구단백E(TIgE)여무명학기출질병인동반복성폐염적관계。방법선취76례무명학기출질병반복성폐염급72례단차폐염환인작위관찰조，인동보건문진체검적60명인동작위대조조，측정삼조혈청25-(OH)D급총면역구단백E(TIgE)함량。결과반복폐염조혈청25-(OH)D수평명현저우단차폐염조화대조조，차이유통계학의의(P<0.05)，단차폐염조혈청25-(OH)D화대조조비교，차이무통계학의의(P>0.05)；반복폐염조혈청TIgE함량수평고우단차폐염조화대조조(P<0.05)，단차폐염조화대조조혈청TIgE비교，차이무통계학의의(P>0.05)。결론유생소D결핍가능시인동환반복폐염적유인지일，재림상응가강인동유생소D결핍적예방、진단화치료。
Objective To study the relationship of serum 25-hydroxy vitaminD and total IgE levels in children with re-current Pneumonia but no underlying diseases. Methods Seventy-six children with recurrent pneumonia but no under-lying diseases and seventy-two children with single pneumonia who visited the hospital were divided into lob servation group. Sixty health examination children in child health clinic as a tontrol group. The levels of 25-hydroxy-vitamin D and total IgE were compared. Results Serum 25-hydroxy-vitamin D levels were significantly lower in the re current pneumonia group than those in a single pneumonia group and control group, the differences were statistically significant (P<0.05). Serum 25-hydroxy-vitamin D levels in the a single pneumonia group were lower than those in control group, but the difference were no statistically significant (P>0.05). Serum TIgE levels were significantly higher in the recurrent pneumonia group than those in the single pneumonia group and control group, the differences were statistically significant (P<0.05). Serum TIgE levels in single pneumonia and control, the differences were not statistically significant (P>0.05). Conclusion Vitamin D deficiency may be one of the factors for recurrent Pneumonia in children, attention should be paid in clinic to strengthen the prevention, diagnosis and treatment of vitamin D deficiency.