CAJ | 학술논문

目的：观察地佐辛在眼科全麻手术中超前镇痛的临床应用价值。方法选择全麻下行眼科手术患者122例，ASAⅠ-Ⅱ级，年龄0~11岁。，随机分成两组，地佐辛组(D组，64例)手术开始前静注地佐辛0.1mg/kg；对照组(C组，58例)手术开始前静注等容积生理盐水。记录手术开始前(T0)、给药后5min(T1)、30min(T2)、拔管即刻(T3)、拔管后5min(T4)和拔管后30min(T5)各时间点的收缩压(SBP)、舒张压(DBP)、心率(HR)。按照RSS躁动评级、Ramsay镇静评分及VAS评分记录患者苏醒期间疼痛、躁动发生及不良反应情况。结果两组患儿围手术期血流动力学变化及术后并发症无明显差异，地佐辛组患儿苏醒期躁动、镇静评分、疼痛评分优于对照组(P<0.05)。结论手术开始前静注地佐辛0.1mg/kg，能有效治疗儿童眼病患者苏醒期疼痛和躁动，能很好地抑制拔管期间的应激反应，而且未见有明显不良反应。
목적：관찰지좌신재안과전마수술중초전진통적림상응용개치。방법선택전마하행안과수술환자122례，ASAⅠ-Ⅱ급，년령0~11세。，수궤분성량조，지좌신조(D조，64례)수술개시전정주지좌신0.1mg/kg；대조조(C조，58례)수술개시전정주등용적생리염수。기록수술개시전(T0)、급약후5min(T1)、30min(T2)、발관즉각(T3)、발관후5min(T4)화발관후30min(T5)각시간점적수축압(SBP)、서장압(DBP)、심솔(HR)。안조RSS조동평급、Ramsay진정평분급VAS평분기록환자소성기간동통、조동발생급불량반응정황。결과량조환인위수술기혈류동역학변화급술후병발증무명현차이，지좌신조환인소성기조동、진정평분、동통평분우우대조조(P<0.05)。결론수술개시전정주지좌신0.1mg/kg，능유효치료인동안병환자소성기동통화조동，능흔호지억제발관기간적응격반응，이차미견유명현불량반응。
Objective Observe the dezocine anesthesia in ophthalmic surgery clinical value of preemptive analgesia.Methods 122 patients undergoing Department of ophthalmology operation,ASA gradeⅠ~II,aged 0~11 years old.,were randomly divided into two groups,dezocine group (group D,64 cases)before the operation of intravenous dezocine 0.1mg/kg;control group (group C,58 cases)before the operation of intravenous injection of normal saline.Record before the operation (T0),5 min after Drug Administration (T1),30 min (T2),extubation time (T3),5 min after extubation (T4)and 30 min after extubation(T5)at dif erent time points of the systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR).According to RSS rating,Ramsay sedation scores and VAS scores of agitation during emergence agitation were recorded and the adverse reactions.Results Two patients in peri operation period of hemodynamic changes and postoperative complications had no obvious dif erence,agitation, dezocine group in recovery period sedation score than the control group ( <0.05).Conclusion The operation before the start of intravenous dezocine 0.1mg/kg,can be ef ective in the treatment of eye diseases in children patients in recovery period pain and agitation,can wel inhibit the stress response during extubation,and no obvious adverse reaction.