临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2014年
30期
10-11
,共2页
螺杆菌,幽门%感染%序贯疗法
螺桿菌,幽門%感染%序貫療法
라간균,유문%감염%서관요법
Helicobacter pylori%Infection%Sequential therapy
目的：探讨新序贯疗法治疗难治性幽门螺杆菌（ Hp）感染的治疗疗效。方法选取2011年6月-2013年6月我科收治的经一次标准三联疗法（质子泵抑制剂或铋剂+2种抗生素治疗7d）治疗失败的患者80例，随机分成治疗组和对照组，治疗组40例采用10d新序贯疗法，对照组40例采用10d传统四联疗法。比较两组Hp根除率。结果治疗组Hp根除率为85.0%（34/40），对照组Hp根除率为65.0%（26/40），差异有统计学意义（ P<0.05）。两组均未出现严重不良反应。结论新序贯疗法治疗难治性Hp感染的疗效确切。
目的：探討新序貫療法治療難治性幽門螺桿菌（ Hp）感染的治療療效。方法選取2011年6月-2013年6月我科收治的經一次標準三聯療法（質子泵抑製劑或鉍劑+2種抗生素治療7d）治療失敗的患者80例，隨機分成治療組和對照組，治療組40例採用10d新序貫療法，對照組40例採用10d傳統四聯療法。比較兩組Hp根除率。結果治療組Hp根除率為85.0%（34/40），對照組Hp根除率為65.0%（26/40），差異有統計學意義（ P<0.05）。兩組均未齣現嚴重不良反應。結論新序貫療法治療難治性Hp感染的療效確切。
목적：탐토신서관요법치료난치성유문라간균（ Hp）감염적치료료효。방법선취2011년6월-2013년6월아과수치적경일차표준삼련요법（질자빙억제제혹필제+2충항생소치료7d）치료실패적환자80례，수궤분성치료조화대조조，치료조40례채용10d신서관요법，대조조40례채용10d전통사련요법。비교량조Hp근제솔。결과치료조Hp근제솔위85.0%（34/40），대조조Hp근제솔위65.0%（26/40），차이유통계학의의（ P<0.05）。량조균미출현엄중불량반응。결론신서관요법치료난치성Hp감염적료효학절。
Objective To study the effect of new sequential therapy in the treatment of refractory Helicobacter pylori ( Hp) infection. Methods A total of 80 failure cases treated by standard triple therapy of eradicating Hp in our hospital from June 2011 to June 2013 were selected,then they were randomly divided into treatment group and control group,40 cases in each. Patients in treatment group were treated with 10 days new sequential therapy,while patients in control group were treated with the 10 days traditional quadruple therapy. The Hp eradication rate between the two groups were compared. Results The Hp eradication rate of treatment group was 85. 0%(34/40),that of the control group was 65. 0%(26/40),the difference was statistically significant(P<0. 05). No one of the two groups occurred severe adverse reactions. Conclusion New se-quential therapy has remarkable effect in the treatment of refractory Hp infection.
