中华现代护理杂志
中華現代護理雜誌
중화현대호리잡지
CHINESE JOURNAL OF MODERN NURSING
2014年
30期
3808-3811
,共4页
护理%口炎%金因肽(重组人表皮生长因子外用溶液)%参麦饮
護理%口炎%金因肽(重組人錶皮生長因子外用溶液)%參麥飲
호리%구염%금인태(중조인표피생장인자외용용액)%삼맥음
Nursing%Radioactive mucositis%Gene Time ( Recombinant human epidermal growth factor)%Shenmai decoction
目的：探讨参麦饮联合金因肽（重组人表皮生长因子外用溶液）防治急性放射性口腔黏膜炎的疗效及护理。方法将80例接受放射治疗的头颈部肿瘤患者按随机数字表法分为治疗组和对照组各40例。两组患者放疗时间均为7周，治疗期间将金因肽喷于受照射区域口腔黏膜，治疗组在此基础上加用参麦饮水煎剂口服，比较两组疗效及口腔黏膜情况。结果放射治疗后所有患者均发生了放射性口腔黏膜炎，随着放疗剂量的增加，反应程度加重，第7周末治疗组Ⅲ、Ⅳ度口腔黏膜炎发生率为25．0％（10/40），对照组为40．0％（16/40），两组比较差异有统计学意义（χ2＝14．39，P＜0．05）。治疗组患者总有效率为87．5％，对照组为85．0％，治疗组优于对照组，但差异无统计学意义（χ2＝0．105，P＞0．05）。结论参麦饮联合金因肽可以减轻放射性口腔黏膜炎，提高临床疗效；护理干预有助于患者的康复。
目的：探討參麥飲聯閤金因肽（重組人錶皮生長因子外用溶液）防治急性放射性口腔黏膜炎的療效及護理。方法將80例接受放射治療的頭頸部腫瘤患者按隨機數字錶法分為治療組和對照組各40例。兩組患者放療時間均為7週，治療期間將金因肽噴于受照射區域口腔黏膜，治療組在此基礎上加用參麥飲水煎劑口服，比較兩組療效及口腔黏膜情況。結果放射治療後所有患者均髮生瞭放射性口腔黏膜炎，隨著放療劑量的增加，反應程度加重，第7週末治療組Ⅲ、Ⅳ度口腔黏膜炎髮生率為25．0％（10/40），對照組為40．0％（16/40），兩組比較差異有統計學意義（χ2＝14．39，P＜0．05）。治療組患者總有效率為87．5％，對照組為85．0％，治療組優于對照組，但差異無統計學意義（χ2＝0．105，P＞0．05）。結論參麥飲聯閤金因肽可以減輕放射性口腔黏膜炎，提高臨床療效；護理榦預有助于患者的康複。
목적：탐토삼맥음연합금인태（중조인표피생장인자외용용액）방치급성방사성구강점막염적료효급호리。방법장80례접수방사치료적두경부종류환자안수궤수자표법분위치료조화대조조각40례。량조환자방료시간균위7주，치료기간장금인태분우수조사구역구강점막，치료조재차기출상가용삼맥음수전제구복，비교량조료효급구강점막정황。결과방사치료후소유환자균발생료방사성구강점막염，수착방료제량적증가，반응정도가중，제7주말치료조Ⅲ、Ⅳ도구강점막염발생솔위25．0％（10/40），대조조위40．0％（16/40），량조비교차이유통계학의의（χ2＝14．39，P＜0．05）。치료조환자총유효솔위87．5％，대조조위85．0％，치료조우우대조조，단차이무통계학의의（χ2＝0．105，P＞0．05）。결론삼맥음연합금인태가이감경방사성구강점막염，제고림상료효；호리간예유조우환자적강복。
Objective To explore the effect and nursing care of Shenmai Decoction plus Gene Time ( recombinant human epidermal growth factor ) on the treatment of radiation oral mucositis .Methods Totals of 80 head-and-neck cancer patients receiving radiotherapy were randomly divided into treatment group ( n=40 ) and control group (n=40).The treatment group was treated with Shenmai Decoction in combination with Gene Time spraying on the irradiated oral mucosa after cleaned , while the control group was treated only with Gene Time.The course of treatment of both groups was 7 weeks.The total curative effect of two groups were observed and the nursing methods were summarized .Results As the increasing dose of radiotherapy , the incidence rates ofⅢ-degree and Ⅳ-degree oral mucositis were increased significantly in the two groups (15.0% vs 25.0%, 25.0%vs 40.0%;χ2 =13.08, 10.31, respectively;P<0.05).However, the incidence rate of Ⅲ-degree andⅣ-degree oral mucositis of treatment group was significantly lower than that of control group ( 15 .0% vs 25.0%, 25.0%vs 40.0%;χ2 =9.21,14.39, respectively;P<0.05).And total effective rate of treatment group was significantly better than that of control group ( 87.5% vs 85.0%; χ2 =0.105, P >0.05 ). Conclusions Shenmai Decoction plus Gene Time can reduce the incidence of radioactive oral mucositis and significantly enhance the curative effect .Nursing interventions can improve the rehabilitation of oral mucositis patients.
