CAJ | 학술논문

目的：探讨肝硬化门静脉高压患者输入人血白蛋白的适宜速度。方法选择门静脉高压需输入人血白蛋白的患者58例，均输入20％人血白蛋白50 ml，采用抛硬币发随机将患者分为对照组（n＝30）和实验组（n＝28）。对照组患者输注速度为25 gtt/min，输入时间为45 min；实验组输注速度为33 gtt/min，输入时间为30 min。采用彩色多普勒超声诊断仪测量不同时间点门静脉内径（ Dpv）、平均血流速度（Vpv）、血流量（Qpv）及门静脉压力，比较两组差异。结果对照组输入白蛋白结束时，Dpv为（13．03±2．01）mm，Vpv为（9．40±2．06）cm/s，Qpv为（782．29±313．02）ml/min，门静脉压力为（2．747±0．348）kPa，与实验组比较差异均无统计学意义（t 值分别为-0．04，0．81，0．46，0．55；P ＞0．05）。结论在30 min内给肝硬化门静脉高压患者输入20％人血白蛋白50ml是可行的。
목적：탐토간경화문정맥고압환자수입인혈백단백적괄의속도。방법선택문정맥고압수수입인혈백단백적환자58례，균수입20％인혈백단백50 ml，채용포경폐발수궤장환자분위대조조（n＝30）화실험조（n＝28）。대조조환자수주속도위25 gtt/min，수입시간위45 min；실험조수주속도위33 gtt/min，수입시간위30 min。채용채색다보륵초성진단의측량불동시간점문정맥내경（ Dpv）、평균혈류속도（Vpv）、혈류량（Qpv）급문정맥압력，비교량조차이。결과대조조수입백단백결속시，Dpv위（13．03±2．01）mm，Vpv위（9．40±2．06）cm/s，Qpv위（782．29±313．02）ml/min，문정맥압력위（2．747±0．348）kPa，여실험조비교차이균무통계학의의（t 치분별위-0．04，0．81，0．46，0．55；P ＞0．05）。결론재30 min내급간경화문정맥고압환자수입20％인혈백단백50ml시가행적。
Objective To explore the suitable human albumin infusion speed in the liver cirrhosis patients with portal hypertension .Methods Fifty-eight portal hypertension patients need to infusion human albumin(50 ml,20%) were chosen and divided into the control group (n =30) and the experimental group ( n=28) by using the coin toss method .The control group received the infusion speed of 25 gtt/min for 45 min, and the experimental group received the infusion speed of 33 gtt/min for 30 min.The portal vein inside diameter (Dpv), mean blood flow velocity (Vpv), blood flow volume (Qpv) and the portal vein pressure measured by the color doppler ultrasound diagnostic instrument were compared at different times between two groups .Results At the end of the infusion, the Dpv,Vpv,Qpv and the portal vein pressure in the control group were (13.03 ± 2.01)mm,(9.40 ±2.06)cm/s,(782.29 ±313.02)ml/min and (2.747 ±0.348)kPa respectively, compared with the experimental group, and the differences were not statistically significant (t=-0.04,0.81,0.46,0.55, respectively;P>0.05).Conclusions It is feasible to input 10 g human albumin (50 ml,20%) during 30 min for the portal hypertension patients .