医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
31期
43-43
,共1页
丙泊酚%七氟醚%术后认知功能障碍
丙泊酚%七氟醚%術後認知功能障礙
병박분%칠불미%술후인지공능장애
Propofol%Sevoflurane%Postoperative cognitive dysfunction
目的比较丙泊酚和七氟醚对老年患者术后早期认知功能的影响。方法筛选年龄≥65岁，ASAⅠ~Ⅱ级的患者62例行择期胸腹部手术，随机分为丙泊酚组和七氟醚组，每组31例。患者术前及术后6 h、12 h、24 h和48h均采用MMSE评价认知功能。结果术后6h、12h、24h丙泊酚组和七氟醚组MMSE评分比较，差异显著(P<0.05)，且随时间的延长，POCD得到改善，术后48 h ,基本恢复正常。结论丙泊酚和七氟醚均可降低老年患者术后早期的认知功能，但七氟醚比丙泊酚认知功能恢复快。
目的比較丙泊酚和七氟醚對老年患者術後早期認知功能的影響。方法篩選年齡≥65歲，ASAⅠ~Ⅱ級的患者62例行擇期胸腹部手術，隨機分為丙泊酚組和七氟醚組，每組31例。患者術前及術後6 h、12 h、24 h和48h均採用MMSE評價認知功能。結果術後6h、12h、24h丙泊酚組和七氟醚組MMSE評分比較，差異顯著(P<0.05)，且隨時間的延長，POCD得到改善，術後48 h ,基本恢複正常。結論丙泊酚和七氟醚均可降低老年患者術後早期的認知功能，但七氟醚比丙泊酚認知功能恢複快。
목적비교병박분화칠불미대노년환자술후조기인지공능적영향。방법사선년령≥65세，ASAⅠ~Ⅱ급적환자62례행택기흉복부수술，수궤분위병박분조화칠불미조，매조31례。환자술전급술후6 h、12 h、24 h화48h균채용MMSE평개인지공능。결과술후6h、12h、24h병박분조화칠불미조MMSE평분비교，차이현저(P<0.05)，차수시간적연장，POCD득도개선，술후48 h ,기본회복정상。결론병박분화칠불미균가강저노년환자술후조기적인지공능，단칠불미비병박분인지공능회복쾌。
Objective To compare the ef ects of propofol and sevoflurane on early cognitive function for elderly patients. Methods 62 patients over the age of 65, ASA Ⅰ~II, and thoracic and abdominal operation were screened, they were divided into propofol group and sevoflurane group, each group had 31 cases. Pre-and postoperative in 6 h, 12 h, 24h and 48h conditions of patients as wel as MMSE were rated. Results Patients were used propofol and sevoflurane with 6h, 12h, 24h hours ,Their MMSE score had significant dif erence ( <0.05), and with the extension of time, POCD could be improved and got back to normal after 48h.Conclusion Propofol and sevoflurane could reduce the early cognitive function for elderly patients, but cognitive function recovered more quickly for sevoflurane than propofol.
