CAJ | 학술논문

目的自发性破裂出血是原发性肝癌最严重并发症之一，但其是否可影响肝癌患者远期生存率尚缺乏足够临床资料佐证。本研究比较了合并自发破裂出血肝癌和同期无破裂出血肝癌治疗的预后差异。方法回顾性分析本院自2010年1月~2011年11月肝癌手术切除患者共176例，其中肝癌自发破裂组(22例)，未破裂组(154例)，随访24个月，观察两组患者生存率的差异。结果合并肝癌自发破裂组患者和未破裂组患者手术切除后1年生存率分别为52.6%和76.4%，2年生存率分别为27.3%和42.9%，两组1年和2年生存率具有显著统计学差异(<0.05)。结论肿瘤自发破裂是影响肝癌早期预后的重要危险因素。
목적자발성파렬출혈시원발성간암최엄중병발증지일，단기시부가영향간암환자원기생존솔상결핍족구림상자료좌증。본연구비교료합병자발파렬출혈간암화동기무파렬출혈간암치료적예후차이。방법회고성분석본원자2010년1월~2011년11월간암수술절제환자공176례，기중간암자발파렬조(22례)，미파렬조(154례)，수방24개월，관찰량조환자생존솔적차이。결과합병간암자발파렬조환자화미파렬조환자수술절제후1년생존솔분별위52.6%화76.4%，2년생존솔분별위27.3%화42.9%，량조1년화2년생존솔구유현저통계학차이(<0.05)。결론종류자발파렬시영향간암조기예후적중요위험인소。
Objective Spontaneous rupture is one of the most vital complications of hepacellular carcinoma (HCC), whether the rupture can reduce the survival rate of the patients with HCC is stil short of decisive evidence.The aim of this study was to compare spontaneous rupture and unrupture of the patients prognosis with HCC. Methods We retrospectively investigated 22 cases with HCC rupture and 154 cases with unrupture, and made a 24-month fol ow-up.After the accomplishment of the 24-month fol ow-up, we analyzed the survival rates of the two groups. Results The 12-month survival rates of the cases with and without rupture were 52.6%and 76.4%, and the 24-month survival rates were 27.3%and 42.9%respectively. A significant dif erence of the 12-and 24-month survival rates existed among the rupture and unrupture groups ( <0.05). Conclusion Spontaneous rupture is an important risk factor for the patients prognosis with hepatocellular carcinoma.