CAJ | 학술논문

目的：探讨老年2型糖尿病和（或）合并短暂性脑缺血发作（TIA）患者血浆同型半胱氨酸水平的变化及临床意义。方法选择单纯老年2型糖尿病患者作为A组；单纯老年TIA患者作为B组；老年2型糖尿病合并TIA患者作为C组；另选同期健康老年体检者作为对照组D组，测定全部研究对象空腹血浆同型半胱氨酸的浓度，并进行比较。结果 B组、C组血浆同型半胱氨酸水平均较对照组D组明显升高，差异有统计学意义（P<0.01）；A组与D组、C组与B组比较差异无统计学意义（P>0.05）。结论单纯老年TIA患者或老年2型糖尿病合并TIA患者血浆同型半胱氨酸水平明显升高。
목적：탐토노년2형당뇨병화（혹）합병단잠성뇌결혈발작（TIA）환자혈장동형반광안산수평적변화급림상의의。방법선택단순노년2형당뇨병환자작위A조；단순노년TIA환자작위B조；노년2형당뇨병합병TIA환자작위C조；령선동기건강노년체검자작위대조조D조，측정전부연구대상공복혈장동형반광안산적농도，병진행비교。결과 B조、C조혈장동형반광안산수평균교대조조D조명현승고，차이유통계학의의（P<0.01）；A조여D조、C조여B조비교차이무통계학의의（P>0.05）。결론단순노년TIA환자혹노년2형당뇨병합병TIA환자혈장동형반광안산수평명현승고。
Objective Explore the elderly type 2 diabetes and its merger TIA plasma homocysteine levels and the clinical significance.Method Patients who had got old aged Type2 diabetes alone were chosen as group A. Patients who had got old age TIA alone were chosen as group B. Patients who had got old age Type 2 diabetes combined TIA were chosen as group C. At the same time, same kind physically examined healthy person were chonsen as group D . The concentration of cysteine(Hcy) in blood plasma in fasting was detected, the level of Hcy was compared each other for the four groups.Results The level of plasma Hcy in group B and C was higher than that in group D There was statistically significance for the difference(P<0.01). There was statistically significance for the difference for group A and D, group C and B(P>0.05).Conclusion Elderly patients with TIA alone or elderly type 2 diabetic patients combine with TIA could increase the level or same type of cysteine in blood plasma.