中国全科医学
中國全科醫學
중국전과의학
CHINESE GENERAL PRACTICE
2014年
32期
3827-3830
,共4页
屈健%刘卫洪%王江平%丁国富%王勤章
屈健%劉衛洪%王江平%丁國富%王勤章
굴건%류위홍%왕강평%정국부%왕근장
输尿管结石%白细胞计数%C 反应蛋白质%疼痛测定
輸尿管結石%白細胞計數%C 反應蛋白質%疼痛測定
수뇨관결석%백세포계수%C 반응단백질%동통측정
Ureteral calculi%Leukocyte count%C - reactive protein%Pain measurement
背景输尿管结石的发病率和患病率逐年增加,其大多数可自行排出,但目前预测结石自行排出的方法尚不完善。目的通过前瞻性研究探讨血白细胞计数、C 反应蛋白(CRP)水平及肾绞痛疼痛分级对输尿管结石自行排出的影响。方法采用简单随机抽样法选取2013年1-8月因肾绞痛在石河子大学医学院第一附属医院就诊的符合入选标准的233例输尿管结石患者的临床资料。记录患者的年龄、性别、体质指数(BMI)、疼痛分级、实验室检查指标、B 超或 CT 影像学资料。1个月后根据患者结石的排出情况分为排石组和未排石组。采用 Logistic 回归分析筛选影响因素;绘制 ROC 曲线确定血白细胞计数预测输尿管结石自行排出的最佳截点。结果138例患者(排石组)输尿管结石自行排出,排石率为59.23%;95例患者(未排石组)输尿管结石未排出。两组患者的结石大小及位置、年龄、疼痛分级、血白细胞计数、中性粒细胞分数、中性粒细胞计数、淋巴细胞分数、CRP 水平间差异有统计学意义( P <0.05)。Logistic 回归分析显示,结石大小、血白细胞计数、CRP 水平、结石位置是输尿管结石自行排出的独立影响因素(OR =0.028、1.736、0.557、1.569,P <0.05)。根据 ROC 曲线,血白细胞计数预测输尿管结石自行排出的截点为9.10×109/ L,灵敏度和特异度分别为0.70和0.58。结论与结石大小及位置一样,血白细胞计数和 CRP 水平可作为预测输尿管结石自行排出的独立影响因素。血白细胞计数<9.10×109/ L 的患者结石排出率低,建议直接行输尿管镜治疗。
揹景輸尿管結石的髮病率和患病率逐年增加,其大多數可自行排齣,但目前預測結石自行排齣的方法尚不完善。目的通過前瞻性研究探討血白細胞計數、C 反應蛋白(CRP)水平及腎絞痛疼痛分級對輸尿管結石自行排齣的影響。方法採用簡單隨機抽樣法選取2013年1-8月因腎絞痛在石河子大學醫學院第一附屬醫院就診的符閤入選標準的233例輸尿管結石患者的臨床資料。記錄患者的年齡、性彆、體質指數(BMI)、疼痛分級、實驗室檢查指標、B 超或 CT 影像學資料。1箇月後根據患者結石的排齣情況分為排石組和未排石組。採用 Logistic 迴歸分析篩選影響因素;繪製 ROC 麯線確定血白細胞計數預測輸尿管結石自行排齣的最佳截點。結果138例患者(排石組)輸尿管結石自行排齣,排石率為59.23%;95例患者(未排石組)輸尿管結石未排齣。兩組患者的結石大小及位置、年齡、疼痛分級、血白細胞計數、中性粒細胞分數、中性粒細胞計數、淋巴細胞分數、CRP 水平間差異有統計學意義( P <0.05)。Logistic 迴歸分析顯示,結石大小、血白細胞計數、CRP 水平、結石位置是輸尿管結石自行排齣的獨立影響因素(OR =0.028、1.736、0.557、1.569,P <0.05)。根據 ROC 麯線,血白細胞計數預測輸尿管結石自行排齣的截點為9.10×109/ L,靈敏度和特異度分彆為0.70和0.58。結論與結石大小及位置一樣,血白細胞計數和 CRP 水平可作為預測輸尿管結石自行排齣的獨立影響因素。血白細胞計數<9.10×109/ L 的患者結石排齣率低,建議直接行輸尿管鏡治療。
배경수뇨관결석적발병솔화환병솔축년증가,기대다수가자행배출,단목전예측결석자행배출적방법상불완선。목적통과전첨성연구탐토혈백세포계수、C 반응단백(CRP)수평급신교통동통분급대수뇨관결석자행배출적영향。방법채용간단수궤추양법선취2013년1-8월인신교통재석하자대학의학원제일부속의원취진적부합입선표준적233례수뇨관결석환자적림상자료。기록환자적년령、성별、체질지수(BMI)、동통분급、실험실검사지표、B 초혹 CT 영상학자료。1개월후근거환자결석적배출정황분위배석조화미배석조。채용 Logistic 회귀분석사선영향인소;회제 ROC 곡선학정혈백세포계수예측수뇨관결석자행배출적최가절점。결과138례환자(배석조)수뇨관결석자행배출,배석솔위59.23%;95례환자(미배석조)수뇨관결석미배출。량조환자적결석대소급위치、년령、동통분급、혈백세포계수、중성립세포분수、중성립세포계수、림파세포분수、CRP 수평간차이유통계학의의( P <0.05)。Logistic 회귀분석현시,결석대소、혈백세포계수、CRP 수평、결석위치시수뇨관결석자행배출적독립영향인소(OR =0.028、1.736、0.557、1.569,P <0.05)。근거 ROC 곡선,혈백세포계수예측수뇨관결석자행배출적절점위9.10×109/ L,령민도화특이도분별위0.70화0.58。결론여결석대소급위치일양,혈백세포계수화 CRP 수평가작위예측수뇨관결석자행배출적독립영향인소。혈백세포계수<9.10×109/ L 적환자결석배출솔저,건의직접행수뇨관경치료。
Background It has been reported that the prevalence and incidence of ureteral calculi(UC) have in-creased by years. Most UCs can be discharged spontaneously. But the method of predicting self - discharge remains unperfect. Objective To explore the effects of blood cell count(WBCC),C - reactive protein(CRP)and renal colic pain rating on self- discharging UCs. Methods From January to August 2013,in the First Affiliated Hospital of Shihezi University,233 UC pa-tients'clinical data were collected. Their age,gender,BMI,pain grading,laboratory parameters,B ultrasound or CT imaging data were recorded. The patients were divided,according to stone discharge after 1 month,into groups UC - discharging,non- UC - discharging. Logistic regression analysis was used to screen influencing factors;ROC curve drawn to determine WBCC predicting the best diagnostic cut - off point of UC self - discharge. Results A total of 138 patients self - discharged UC,the discharging rate was 59. 23% ,95 did not self - discharged. There was significant difference in stone size,location,age,pain grading,WBCC,neutrophil percentage and count,lymphocyte percentage,CRP between 2 groups(P < 0. 05). Logistic re-gression analysis showed that WBCC,CRP,stone size and location were factors influencing self - discharging UC(OR = 0. 028, 1. 736,0. 557,1. 569,P < 0. 05). By ROC curve,the cut - off point WBCC predicting UC self - discharging was 9. 10 × 109 / L,the sensitivity and specificity were 0. 70 and 0. 58. Conclusion Like stone size and location,WBCC and CRP can be used as independent factors predicting UC self - discharging. The patients with WBC < 9. 10 × 109 / L and low stone discharging rate should be given ureteroscopy treatment.