中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2014年
7期
158-160
,共3页
全身麻醉%右美托咪啶%苏醒期%应激反应%寒颤
全身痳醉%右美託咪啶%囌醒期%應激反應%寒顫
전신마취%우미탁미정%소성기%응격반응%한전
general anesthesia%dexmedetomidine%recovery period%stress reaction%shivering
目的：探究右美托咪啶在静吸复合全身麻醉方案中对患者苏醒期应激反应及寒颤发生率的影响，并为临床麻醉恢复质量积累经验。方法选取2010年3月～2013年4月福建医科大学附属医院收治的76例手术患者，利用随机双盲法分为研究组和对照组（n＝38）。2组患者均进行静吸复合全身麻醉，其中研究组在麻醉过程中给予右美托嘧啶静脉泵注，对照组则给予同剂量、同速率的生理盐水静脉泵注。比较2组患者苏醒期MAAS（肌肉活动评分）、HR（心率）、MAP（平均动脉压）及寒颤发生率。结果研究组拔管后5 min的MAAS评分低于对照组（P＜0.05）；研究组在拔管即时、拔管后30 min的MAP和HR值均低于对照组（P＜0.05）。研究组寒颤发生率低于对照组，且寒颤时间短于对照组（P＜0.05）。结论右美托咪啶应用于静吸复合全麻患者，能有效降低其苏醒期应激程度，减少寒颤发生率，利于患者恢复期生命体征的稳定。
目的：探究右美託咪啶在靜吸複閤全身痳醉方案中對患者囌醒期應激反應及寒顫髮生率的影響，併為臨床痳醉恢複質量積纍經驗。方法選取2010年3月～2013年4月福建醫科大學附屬醫院收治的76例手術患者，利用隨機雙盲法分為研究組和對照組（n＝38）。2組患者均進行靜吸複閤全身痳醉，其中研究組在痳醉過程中給予右美託嘧啶靜脈泵註，對照組則給予同劑量、同速率的生理鹽水靜脈泵註。比較2組患者囌醒期MAAS（肌肉活動評分）、HR（心率）、MAP（平均動脈壓）及寒顫髮生率。結果研究組拔管後5 min的MAAS評分低于對照組（P＜0.05）；研究組在拔管即時、拔管後30 min的MAP和HR值均低于對照組（P＜0.05）。研究組寒顫髮生率低于對照組，且寒顫時間短于對照組（P＜0.05）。結論右美託咪啶應用于靜吸複閤全痳患者，能有效降低其囌醒期應激程度，減少寒顫髮生率，利于患者恢複期生命體徵的穩定。
목적：탐구우미탁미정재정흡복합전신마취방안중대환자소성기응격반응급한전발생솔적영향，병위림상마취회복질량적루경험。방법선취2010년3월～2013년4월복건의과대학부속의원수치적76례수술환자，이용수궤쌍맹법분위연구조화대조조（n＝38）。2조환자균진행정흡복합전신마취，기중연구조재마취과정중급여우미탁밀정정맥빙주，대조조칙급여동제량、동속솔적생리염수정맥빙주。비교2조환자소성기MAAS（기육활동평분）、HR（심솔）、MAP（평균동맥압）급한전발생솔。결과연구조발관후5 min적MAAS평분저우대조조（P＜0.05）；연구조재발관즉시、발관후30 min적MAP화HR치균저우대조조（P＜0.05）。연구조한전발생솔저우대조조，차한전시간단우대조조（P＜0.05）。결론우미탁미정응용우정흡복합전마환자，능유효강저기소성기응격정도，감소한전발생솔，리우환자회복기생명체정적은정。
Objective To explore the effect of dexmedetomidine on the stress reaction and incidence of shivering in intravenous inhalation combined anesthesia scheme,and to improve the quality of anesthesia recovery accumulate experience.Methods 76 patients in Affiliated Union Hospital of Fujian Medical University from 2010 March to 2013 April were divided into study group and control group using random double blind method(n=38).Two groups of patients were underwent intravenous inhalation combined anesthesia,the research group in the process of anesthesia administered dexmedetomidine intravenous infusion,the control group was given normal saline intravenous infusion of the same dose,the same rate.The recovery period MAAS (muscle activity score),HR (heart rate),MAP (mean arterial pressure)and the incidence of shivering of two groups were observed and compared.Results The MAAS score on 5 min after extubation of study group was lower than that of control group (P<0.05);the MAP and HR values immediately in the drawing or after extubation 30 min in study group were lower than control group (P<0.05 ).The incidence of shivering and the chill time in study group was lower and shorter than control group (P<0.05).Conclusion Dexmedetomidine could effectively reduce the recovery period of stress level,and reduce the incidence of shivering in treatment of patients with intravenous inhalation combined anesthesia,It is conducive to patient of vital signs stable in recovery period.
