中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2014年
7期
156-157
,共2页
地佐辛%芬太尼%术后镇痛%腹部手术
地佐辛%芬太尼%術後鎮痛%腹部手術
지좌신%분태니%술후진통%복부수술
dezocine%fentanyl%postoperative analgesia%abdominal surgery
目的：探讨地佐辛在腹部全麻手术术后镇痛效果。方法80例（ASAⅠ～Ⅱ级）全麻腹部手术要求术后镇痛的患者，按术后镇痛药物不同随机均分为2组（n＝40）：地佐辛组（D组）地佐辛0.6 mg/kg＋昂丹司琼4mg加0.9％氯化钠至100 mL，负荷剂量经静脉患者自控镇痛（intravenous patient-controlled analgesia，PCIA）；芬太尼组（F组）芬太尼12μg/kg＋昂丹司琼4mg加0.9％氯化钠至100 mL，负荷剂量加PCIA，记录术后2、4、8、12、24、48 h的视觉模拟评分（visual analog scale，VAS）及Ramsay镇静评分。结果2组VAS评分及Ramsay评分差异无统计学意义，而不良反应发生率芬太尼组显著高于地佐辛组（P＜0.01）。结论地佐辛组可为腹部全麻手术后患者提供较安全和舒适的镇痛作用。
目的：探討地佐辛在腹部全痳手術術後鎮痛效果。方法80例（ASAⅠ～Ⅱ級）全痳腹部手術要求術後鎮痛的患者，按術後鎮痛藥物不同隨機均分為2組（n＝40）：地佐辛組（D組）地佐辛0.6 mg/kg＋昂丹司瓊4mg加0.9％氯化鈉至100 mL，負荷劑量經靜脈患者自控鎮痛（intravenous patient-controlled analgesia，PCIA）；芬太尼組（F組）芬太尼12μg/kg＋昂丹司瓊4mg加0.9％氯化鈉至100 mL，負荷劑量加PCIA，記錄術後2、4、8、12、24、48 h的視覺模擬評分（visual analog scale，VAS）及Ramsay鎮靜評分。結果2組VAS評分及Ramsay評分差異無統計學意義，而不良反應髮生率芬太尼組顯著高于地佐辛組（P＜0.01）。結論地佐辛組可為腹部全痳手術後患者提供較安全和舒適的鎮痛作用。
목적：탐토지좌신재복부전마수술술후진통효과。방법80례（ASAⅠ～Ⅱ급）전마복부수술요구술후진통적환자，안술후진통약물불동수궤균분위2조（n＝40）：지좌신조（D조）지좌신0.6 mg/kg＋앙단사경4mg가0.9％록화납지100 mL，부하제량경정맥환자자공진통（intravenous patient-controlled analgesia，PCIA）；분태니조（F조）분태니12μg/kg＋앙단사경4mg가0.9％록화납지100 mL，부하제량가PCIA，기록술후2、4、8、12、24、48 h적시각모의평분（visual analog scale，VAS）급Ramsay진정평분。결과2조VAS평분급Ramsay평분차이무통계학의의，이불량반응발생솔분태니조현저고우지좌신조（P＜0.01）。결론지좌신조가위복부전마수술후환자제공교안전화서괄적진통작용。
Objective To investigate analgesia of dezocine in abdominal anesthesia postoperative.Methods 80 cases (ASA I ~II)abdominal surgery under general anesthesia patients required postoperative analgesia,according to different postoperative analgesia drug,patients were randomly divided into 2 groups:dezocine group (group D),dezocine 0.6 mg/kg+ondansetron 4mg plus 0.9% sodium chloride to 100 mL,loading dose of intravenous patient controlled analgesia (PCIA);fentanyl group (group F),fentanyl 12 g/kg+ondansetron 4mg plus 0.9% sodium chloride to 100 mL,loading dose plus PCIA,recorded after 2,4,8,12,24,48 h visual analog scale (VAS)and Ramsay sedation score.Results The 2 groups were not statistically significant differences in VAS score and Ramsay score,and the incidence of adverse reaction of fentanyl group was significantly higher than that of dezocine group (P<0.01).Conclusion Dezocine group could provide analgesia safe and comfortable for patients after abdominal operation under general anesthesia.
