中国生化药物杂志
中國生化藥物雜誌
중국생화약물잡지
CHINESE JOURNAL OF BIOCHEMICAL PHARMACEUTICS
2014年
7期
111-113
,共3页
脑苷肌肽%丹参川芎嗪注射液%急性脑梗死
腦苷肌肽%丹參川芎嗪註射液%急性腦梗死
뇌감기태%단삼천궁진주사액%급성뇌경사
cattle encephalon glycoside and ignotin%salvia ligustrazine injection%acute cerebral infarction
目的：研究脑苷肌肽联合丹参川芎嗪注射液对急性脑梗死的临床疗效。方法选择2012年7月～2013年10月厦门市中医院收治的50例急性脑梗死患者，具体随机方法分为观察组和对照组。观察组25例患者，采用脑苷肌肽联合丹参川芎嗪注射液治疗；对照组25例患者，仅采用丹参川芎嗪注射液治疗。治疗2周后，观察比较2组患者的临床疗效、血液流变学指标（全血黏度、血小板聚集率、血浆比粘度）、神经功能的缺损程度以及生活能力评分。结果2组患者一般临床资料差异无统计意义；治疗后，观察组和对照组的总有效率分别为92.00％和60.00％，2组比较差异有统计学意义（u＝2.4129，P＝0.0158）；治疗后，观察组患者的全血黏度（高切、低切）均低于对照组，2组患者比较差异有统计学意义（P＜0.05）；观察组患者的血小板聚集率低于对照组，2组患者比较差异有统计学意义（t＝0.5632，P＝0.5759）；观察组患者的血浆比粘度低于对照组，2组比较差异有统计学意义（t＝3.7682，P＝0.0004）；观察组患者神经功能的缺损程度以及生活能力的评分均低于对照组，2组比较差异均有统计学意义（P＜0.05）。结论脑苷肌肽联合丹参川芎嗪注射液治疗急性脑梗死临床疗效较单独应用丹参川芎嗪注射液效果更好。
目的：研究腦苷肌肽聯閤丹參川芎嗪註射液對急性腦梗死的臨床療效。方法選擇2012年7月～2013年10月廈門市中醫院收治的50例急性腦梗死患者，具體隨機方法分為觀察組和對照組。觀察組25例患者，採用腦苷肌肽聯閤丹參川芎嗪註射液治療；對照組25例患者，僅採用丹參川芎嗪註射液治療。治療2週後，觀察比較2組患者的臨床療效、血液流變學指標（全血黏度、血小闆聚集率、血漿比粘度）、神經功能的缺損程度以及生活能力評分。結果2組患者一般臨床資料差異無統計意義；治療後，觀察組和對照組的總有效率分彆為92.00％和60.00％，2組比較差異有統計學意義（u＝2.4129，P＝0.0158）；治療後，觀察組患者的全血黏度（高切、低切）均低于對照組，2組患者比較差異有統計學意義（P＜0.05）；觀察組患者的血小闆聚集率低于對照組，2組患者比較差異有統計學意義（t＝0.5632，P＝0.5759）；觀察組患者的血漿比粘度低于對照組，2組比較差異有統計學意義（t＝3.7682，P＝0.0004）；觀察組患者神經功能的缺損程度以及生活能力的評分均低于對照組，2組比較差異均有統計學意義（P＜0.05）。結論腦苷肌肽聯閤丹參川芎嗪註射液治療急性腦梗死臨床療效較單獨應用丹參川芎嗪註射液效果更好。
목적：연구뇌감기태연합단삼천궁진주사액대급성뇌경사적림상료효。방법선택2012년7월～2013년10월하문시중의원수치적50례급성뇌경사환자，구체수궤방법분위관찰조화대조조。관찰조25례환자，채용뇌감기태연합단삼천궁진주사액치료；대조조25례환자，부채용단삼천궁진주사액치료。치료2주후，관찰비교2조환자적림상료효、혈액류변학지표（전혈점도、혈소판취집솔、혈장비점도）、신경공능적결손정도이급생활능력평분。결과2조환자일반림상자료차이무통계의의；치료후，관찰조화대조조적총유효솔분별위92.00％화60.00％，2조비교차이유통계학의의（u＝2.4129，P＝0.0158）；치료후，관찰조환자적전혈점도（고절、저절）균저우대조조，2조환자비교차이유통계학의의（P＜0.05）；관찰조환자적혈소판취집솔저우대조조，2조환자비교차이유통계학의의（t＝0.5632，P＝0.5759）；관찰조환자적혈장비점도저우대조조，2조비교차이유통계학의의（t＝3.7682，P＝0.0004）；관찰조환자신경공능적결손정도이급생활능력적평분균저우대조조，2조비교차이균유통계학의의（P＜0.05）。결론뇌감기태연합단삼천궁진주사액치료급성뇌경사림상료효교단독응용단삼천궁진주사액효과경호。
Objective To evaluate the clinical efficacy of cattle encephalon glycoside and ignotin with salviae miltiorrhizae and ligustrazine hydrochloride injection for acute cerebral infarction.Methods 50 patients with acute cerebral infarction from July 2012 to October 2013 admitted in our hospital were randomly divided into observation group and control group.Observation group had 25 patients,they were treated with cattle encephalon glycoside and ignotin with salviae miltiorrhizae and ligustrazine hydrochloride injection.Control group had 25 patients,they were treated with only salviae miltiorrhizae and ligustrazine hydrochloride injection.After two groups'treatment,the clinical efficacy,indicators of hemorheology (include whole blood viscosity,platelet aggregation and plasma viscosity),neurological deficiency score and activity of daily life were observed and compared.Results There was no significant difference in the clinical data between two group.After treatment,the total efficiency rate in observation group and control group were 92.00% and 60.00%,separately,the difference between two group was significant (u=2.4129,P=0.0158);the whole blood viscosity (high cut, low cut)of observation group were shorter than control group(P<0.05 );platelet aggregation of observation group were shorter than control group(t=0.5632,P=0.5759);plasma viscosity of observation group were shorter than control group(t=3.7682,P=0.0004);the neurological deficiency score and activity of daily life of observation group were shorter than control group(t =3.7682,P=0.0004).Conclusion The clinical efficacy of cattle encephalon glycoside and ignotin with salviae miltiorrhizae and ligustrazine hydrochloride injection for acute cerebral infarction is well.
