CAJ | 학술논문

多发性骨髓瘤(multiple myeloma，MM)是一种浆细胞恶性肿瘤，随着研究的深入，对MM的诊断不再局限于骨髓活检与影像学检查，而是向血清游离轻链、细胞遗传学和分子生物学检测方向发展，这使医务人员对该疾病的发生机制有了更深的了解，同时为预后评估提供了重要依据。下面主要从MM的实验室检查、诊断标准和分期3个方面对近年MM的诊断及其进展进行综述。
다발성골수류(multiple myeloma，MM)시일충장세포악성종류，수착연구적심입，대MM적진단불재국한우골수활검여영상학검사，이시향혈청유리경련、세포유전학화분자생물학검측방향발전，저사의무인원대해질병적발생궤제유료경심적료해，동시위예후평고제공료중요의거。하면주요종MM적실험실검사、진단표준화분기3개방면대근년MM적진단급기진전진행종술。
Multiple myeloma (MM) is a plasma cell malignancy. With the development of the understanding of MM, the diagnosis is no more limited to bone marrow biopsy and imageological examination. Serum free light chain, cytogenetic analysis and molecular biology study are becoming increasingly widely used, which give us a deeper under-standing of the mechanisms of MM and provide us with a clearer prognosis evaluation. Here is to make a review of the diagnosis and its development of MM from laboratory examination, diagnosis criteria and classiifcation.