CAJ | 학술논문

未足月胎膜早破(PPROM)是指孕龄<37孕周且胎膜在临产前发生自发性破裂。据统计，由PPROM导致的早产发生率为30%~40%，且孕龄越小，破膜时间越早，早产儿病死率越高，同时也可增加孕产妇感染率及围生儿病死率，故PPROM的治疗是产科亟待解决的问题。目前，有关 PPROM的治疗可分为期待疗法和终止妊娠。期待疗法主要包括一般治疗、预防性抗感染、抑制宫缩、促胎肺成熟、因羊水过少行羊膜腔灌注术(AI)以及重新封闭胎膜破口的羊膜腔封闭疗法。笔者拟就目前有关 PPROM的期待疗法及其研究现状进行综述如下。
미족월태막조파(PPROM)시지잉령<37잉주차태막재임산전발생자발성파렬。거통계，유PPROM도치적조산발생솔위30%~40%，차잉령월소，파막시간월조，조산인병사솔월고，동시야가증가잉산부감염솔급위생인병사솔，고PPROM적치료시산과극대해결적문제。목전，유관 PPROM적치료가분위기대요법화종지임신。기대요법주요포괄일반치료、예방성항감염、억제궁축、촉태폐성숙、인양수과소행양막강관주술(AI)이급중신봉폐태막파구적양막강봉폐요법。필자의취목전유관 PPROM적기대요법급기연구현상진행종술여하。
Preterm premature rupture of membranes (PPROM ) is that membranous rupture spontaneously prior to 37 weeks gestation before labor.According to statistics,among the pregnant women of PPROM,the rate of preterm delivery ranges from 30%-40%.And the smaller the weeks of gestation and the earlier the rupture of membrane,the more the mortality of the premature infants happens.At the same time,PPROM also could increase the infection rate of the pregnant women and the mortality of the perinatal infants,so the therapy of PPROM is an urgent problem.At present,the management of PPROM includes expectant management and terminated gestation.Expectant management includes the general treatment, prevention of infection,inhibiting uterine contraction,promoting fetal lung maturity,amnioinfusion (AI) caused by oligohydramnios,and resealed membranes crevasse amniotic cavity closed therapy.This article reviews the literatures on expectant management of PPROM.