CAJ | 학술논문

目的：探讨通过卒中绿色通道建立,缩短院内延迟在急性脑梗死静脉溶栓治疗中的临床价值。方法收集2012年9月~2013年8月本科51例急性脑梗死患者接诊后进入卒中绿色通道,在4.5 h内接受重组组织型纤溶酶原激活物(rt-PA)静脉溶栓的急性脑梗死患者,评价就诊至溶栓时间,溶栓前、溶栓后2 h、14 d NIHSS 评分,溶栓后90 d mRS 评分,并分析危险因素与静脉溶栓预后的相关性。结果51例急性脑梗死患者从接诊至溶栓治疗的平均时间为(62.6±11.7)min,60 min 内接受溶栓治疗24例(47%),44例完全或部分好转出院,院内延迟时间(DNT)<62.6 min 组和>62.6 min 组的 NIHSS 和 mRS 评分的差异明显(P <0.05),即 DNT≤62.6 min 组预后较好。结论卒中绿色通道建立可有效缩短院内延迟时间,增加急性脑梗死患者溶栓治疗机会,具有较高的临床应用价值。
목적：탐토통과졸중록색통도건립,축단원내연지재급성뇌경사정맥용전치료중적림상개치。방법수집2012년9월~2013년8월본과51례급성뇌경사환자접진후진입졸중록색통도,재4.5 h내접수중조조직형섬용매원격활물(rt-PA)정맥용전적급성뇌경사환자,평개취진지용전시간,용전전、용전후2 h、14 d NIHSS 평분,용전후90 d mRS 평분,병분석위험인소여정맥용전예후적상관성。결과51례급성뇌경사환자종접진지용전치료적평균시간위(62.6±11.7)min,60 min 내접수용전치료24례(47%),44례완전혹부분호전출원,원내연지시간(DNT)<62.6 min 조화>62.6 min 조적 NIHSS 화 mRS 평분적차이명현(P <0.05),즉 DNT≤62.6 min 조예후교호。결론졸중록색통도건립가유효축단원내연지시간,증가급성뇌경사환자용전치료궤회,구유교고적림상응용개치。
Objective To explore the clinical value of reducing in-hospital delay in patients with acute is-chemic stroke after intravenous thrombolysis across establishing green channel.Methods 5 1 patients with a-cute ischemic strokes treated by recombinant tissue-type plasminogen activator within 4.5 h from symptoms onset were enrolled in this study.The door-to-needle time (DNT),the National Institute of Health Stroke Scale (NIHSS)score at before thrombolysis therapy,2 h and 7 d after thrombolysis therapy were evaluated.Modified Rankin Scale score(mRS)were evaluated after 30 days.Investigating factors and favorable outcome.Results The median time of DNT was reduced to 62.6 1 1 .7 minutes in 5 1 patients.Proportion of patients presenting ≤60 minutes approved Intravenous thrombolysis was 47%.Hyptension is significantly associated with unfavor-able outcome.Conclusions By establishing green channel,reducing in-hospital delay can provide an opportunity to patients with acute ischemic stroke.